ArticleJournal of clinical medicine2023
"The Pupillary (Hippus) Nystagmus": A Possible Clinical Hallmark to Support the Diagnosis of Vestibular Migraine.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effects of Indirect Pupillary Light Reflex Stimulation With Colored Light on Corneal Specular Microscopy Performance in Dogs.Veterinary ophthalmology · 2026Article
- Quantitative pupillometry as a marker of autonomic dysregulation in vestibular migraine.Journal of oral & facial pain and headache · 2026Article
- Pupillary Nystagmus as an Objective Neuro-Otological Biomarker in Vestibular Migraine: A Quantitative Pupillometric Study.Audiology research · 2026Article
- Can video head impulse testing aid differential assessment of suspected vestibular migraine attacks?Frontiers in neurology · 2026Review
- Pupillary Hippus as a Biomarker: Spectral Signatures and Complexity Approaches in Autonomic and Clinical Contexts.Bioengineering (Basel, Switzerland) · 2025Review
- Cervical Oculopathy: The Cervical Spine Etiology of Visual Symptoms and Eye Diseases-A Hypothesis Exploring Mechanisms Linking the Neck and the Eye.Diagnostics (Basel, Switzerland) · 2025Article
- Non-nystagmus hyperkinetic eye movement disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- The Near Point of Convergence in Patients with Vestibular Migraine.International archives of otorhinolaryngology · 2025Article
- Episodic Vertigo: A Narrative Review Based on a Single-Center Clinical Experience.Audiology research · 2023Article
- Recent Advances in the Diagnosis and Treatment of Vestibular Disorders.Journal of clinical medicine · 2023Article
- Vestibular and Oculomotor Findings in Vestibular Migraine Patients.Audiology research · 2023Article
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Authors and funding
2 authors.
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Abstract
(1) Background: Hippus (which in this paper will be called "Pupillary nystagmus") is a well-known phenomenon which has never been related to any specific pathology, so much so that it can be considered physiological even in the normal subject, and is characterized by cycles of dilation and narrowing of the pupil under constant lighting conditions. The aim of this study is to verify the presence of pupillary nystagmus in a series of patients suffering from vestibular migraine. (2) Methods: 30 patients with dizziness suffering from vestibular migraine (VM), diagnosed according to the international criteria, were evaluated for the presence of pupillary nystagmus and compared with the results obtained in a group of 50 patients complaining of dizziness that was not migraine-related. (3) Results: Among the 30 VM patients, only two cases were found to be negative for pupillary nystagmus. Among the 50 non-migraineurs dizzy patients, three had pupillary nystagmus, while the remaining 47 did not. This resulted in a test sensitivity of 0.93% and a specificity of 0.94%. (4) Conclusion: we propose the consideration of the presence of pupillary nystagmus as an objective sign (present in the inter-critical phase) to be associated with the international diagnostic criteria for the diagnosis of vestibular migraine.
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