Evidence map›Paper›PMID 36902712›Full record

ArticleJournal of clinical medicine2023

Early Gastrointestinal Neuropathy Assessed by Wireless Motility Capsules in Adolescents with Type 1 Diabetes.

Vinni Faber Rasmussen, Mathilde Thrysøe, Páll Karlsson, Esben Thyssen Vestergaard, Kurt Kristensen, Ann-Margrethe Rønholt Christensen, Jens Randel Nyengaard, Astrid Juhl Terkelsen, Christina Brock, Klaus Krogh

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Sweat gland nerve fiber density and association with sudomotor function, symptoms, and risk factors in adolescents with type 1 diabetes.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vinni Faber RasmussenDanish Pain Research Center, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.
Mathilde ThrysøeDanish Pain Research Center, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.ORCID 0000-0002-3557-6566
Páll KarlssonDanish Pain Research Center, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.ORCID 0000-0001-7082-9576
Esben Thyssen VestergaardSteno Diabetes Center Aarhus, Aarhus University Hospital, 8200 Aarhus, Denmark.
Kurt KristensenSteno Diabetes Center Aarhus, Aarhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0002-3912-8234
Ann-Margrethe Rønholt ChristensenDepartment of Pediatrics and Adolescent Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark.
Jens Randel NyengaardCore Centre for Molecular Morphology, Section for Stereology and Microscopy, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.
Astrid Juhl TerkelsenDanish Pain Research Center, Department of Clinical Medicine, Aarhus University, 8200 Aarhus, Denmark.
Christina BrockDepartment of Gastroenterology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Klaus KroghDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, 8200 Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the prevalence of objective signs of gastrointestinal (GI) autonomic neuropathy (AN) in adolescents with type 1 diabetes (T1D). In addition, to investigate associations between objective GI findings and self-reported symptoms or other findings of AN.

methodsFifty adolescents with T1D and 20 healthy adolescents were examined with a wireless motility capsule to assess the total and regional GI transit times and motility index. GI symptoms were evaluated with the GI Symptom Rating Scale questionnaire. AN was evaluated with cardiovascular and quantitative sudomotor axon reflex tests.

resultsThere was no difference in GI transit times in adolescents with T1D and healthy controls. Adolescents with T1D had a higher colonic motility index and peak pressure than the controls, and GI symptoms were associated with low gastric and colonic motility index (all

conclusionsObjective signs of GI neuropathy are common in adolescents with T1D and it seems to require early interventions in patients at high risk of developing GI neuropathy.

Indexed as

adolescentautonomic neuropathygastrointestinal symptomstype 1 diabeteswireless motility capsule

Identifiers

PMID36902712
PMCPMC10003990

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.