Evidence map›Paper›PMID 36902709›Full record

ArticleJournal of clinical medicine2023

Do Cortisol and Dehydroepiandrosterone Influence Motivational Factors for Non-Suicidal Self-Injury in Female Adolescents?

Francesco Maria Piarulli, Anna Margari, Francesco Margari, Emilia Matera, Federica Croce, Flora Furente, Alessandra Gabellone, Maria Giuseppina Petruzzelli

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco Maria PiarulliDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.ORCID 0000-0003-3209-3478
Anna MargariDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.
Francesco MargariDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.
Emilia MateraDepartment of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University "A. Moro", 7016 Bari, Italy.ORCID 0000-0002-7541-0616
Federica CroceDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.
Flora FurenteDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.ORCID 0000-0001-7081-2520
Alessandra GabelloneDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.ORCID 0000-0002-6808-4883
Maria Giuseppina PetruzzelliDepartment of Translational Biomedicine and Neurosciences (DiBraiN), University "A. Moro", 7016 Bari, Italy.ORCID 0000-0003-1734-788X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-suicidal self-injury (NSSI) is a significant public health issue that particularly affects female adolescents usually emerging during puberty, with a subsequent reduction and even remission in the phenomenon later in life. The dysregulation of the hormonal stress response, particularly cortisol and dehydroepiandrosterone sulfate (DHEA-S), whose levels increase markedly during pubertal adrenarche, has been associated with the development and maintenance of a wide range of emotional disorders. Our study aims to investigate whether different cortisol-DHEA-S response patterns could be associated with the main motivational moderators to engage NSSI as well as with urgency and motivation to stop NSSI in a sample of female adolescents. We found significant correlations between stress hormones and several factors that support and sustain NSSI, specifically: cortisol levels and distressing/upsetting urge (r = 0.39 and a

Indexed as

cortisolDHEA-Semotional dysregulationnon-suicidal self-injuryOttawa Self Injury Inventorystress responsetheory of urgency

Identifiers

PMID36902709
PMCPMC10003553

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.