Evidence map›Paper›PMID 36902687›Full record

ArticleJournal of clinical medicine2023

Changes in Bone Metabolism in Patients with Rheumatoid Arthritis during Tumor Necrosis Factor Inhibitor Therapy.

Tanja Janković, Momir Mikov, Jelena Zvekić Svorcan, Ivana Minaković, Jelena Mikov, Ksenija Bošković, Darko Mikić

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanja JankovićMedical Faculty, University of Novi Sad, Special Hospital for Rheumatic Diseases, 21000 Novi Sad, Serbia.ORCID 0000-0002-4882-1794
Momir MikovDepartment of Pharmacology and Toxicology, Medical Faculty, University of Novi Sad, 21000 Novi Sad, Serbia.
Jelena Zvekić SvorcanMedical Faculty, University of Novi Sad, Special Hospital for Rheumatic Diseases, 21000 Novi Sad, Serbia.
Ivana MinakovićMedical Faculty, University of Novi Sad, Health Center "Novi Sad", 21000 Novi Sad, Serbia.ORCID 0000-0002-6784-8618
Jelena MikovMedical Faculty, University of Novi Sad, 21000 Novi Sad, Serbia.
Ksenija BoškovićMedical Faculty, University of Novi Sad, Special Hospital for Rheumatic Diseases, 21000 Novi Sad, Serbia.
Darko MikićPathology and Forensic Medicine Institute, Medical Faculty of the Military Medical Academy, University of Defence, 11000 Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor alpha (TNF-α), which enhances osteoclast activity and bone resorption, is one of the key inflammation mediators in rheumatoid arthritis (RA). The aim of this study was to assess the influence of yearlong TNF-α inhibitor application on bone metabolism. The study sample comprised 50 female patients with RA. Analyses involved the osteodensitometry measurements obtained using a "Lunar" type apparatus and the following biochemical markers from serum: procollagen type 1 N-terminal propeptide (P1NP), beta crosslaps C-terminal telopeptide of collagen type I (b-CTX) by ECLIA method, total and ionized calcium, phosphorus, alkaline phosphatase, parathyroid hormone and vitamin D. Analyses revealed changes in bone mineral density (BMD) at L1-L4 and the femoral neck, with the difference in mean BMD (g/cm

Indexed as

bone metabolismbone mineral densityosteoporosis inhibitor tumor necrosis factor alpharheumatoid arthritis

Identifiers

PMID36902687
PMCPMC10003627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.