Evidence map›Paper›PMID 36902659›Full record

ReviewJournal of clinical medicine2023

Exercise across the Lung Cancer Care Continuum: An Overview of Systematic Reviews.

Lara Edbrooke, Amy Bowman, Catherine L Granger, Nicola Burgess, Shaza Abo, Bronwen Connolly, Linda Denehy

Full text readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. I want to get better; I don't want to just stay at home: a theory-driven qualitative exploration of participation in a home-based lung cancer exercise clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  4. Trial
  5. Review
  6. Observational
  7. Article
  8. Co-Designing Lung Cancer Rehabilitation Services for People Treated With Immunotherapy.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Empowering Recovery: A Co-Designed Intervention to Transform Care for Operable Lung Cancer.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Patients' and carers' views on research priorities in prehabilitation for cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lara EdbrookeDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-4149-5578
Amy BowmanDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0001-8489-4387
Catherine L GrangerDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0001-6169-370X
Nicola BurgessDepartment of Physiotherapy, Austin Health, Melbourne, VIC 3084, Australia.
Shaza AboDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC 3010, Australia.
Bronwen ConnollyWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast BT7 1NN, UK.
Linda DenehyDepartment of Physiotherapy, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0002-2926-8436

Funding

The University of Melbourne 2021ECR097
6 · The paper itself

Abstract

backgroundGrowing evidence supports exercise for people with lung cancer. This overview aimed to summarise exercise intervention efficacy and safety across the care continuum.

methodsEight databases (including Cochrane and Medline) were searched (inception-February 2022) for systematic reviews of RCTs/quasi-RCTs. Eligibility: population-adults with lung cancer; intervention: exercise (e.g., aerobic, resistance) +/- non-exercise (e.g., nutrition); comparator: usual care/non-exercise; primary outcomes: exercise capacity, physical function, health-related quality of life (HRQoL) and post-operative complications. Duplicate, independent title/abstract and full-text screening, data extraction and quality ratings (AMSTAR-2) were completed.

resultsThirty systematic reviews involving between 157 and 2109 participants (n = 6440 total) were included. Most reviews (n = 28) involved surgical participants. Twenty-five reviews performed meta-analyses. The review quality was commonly rated critically low (n = 22) or low (n = 7). Reviews commonly included combinations of aerobic, resistance and/or respiratory exercise interventions. Pre-operative meta-analyses demonstrated that exercise reduces post-operative complications (n = 4/7) and improves exercise capacity (n = 6/6), whilst HRQoL findings were non-significant (n = 3/3). Post-operative meta-analyses reported significant improvements in exercise capacity (n = 2/3) and muscle strength (n = 1/1) and non-significant HRQoL changes (n = 8/10). Interventions delivered to mixed surgical and non-surgical populations improved exercise capacity (n = 3/4), muscle strength (n = 2/2) and HRQoL (n = 3). Meta-analyses of interventions in non-surgical populations demonstrated inconsistent findings. Adverse event rates were low, however, few reviews reported on safety.

conclusionsA large body of evidence supports lung cancer exercise interventions to reduce complications and improve exercise capacity in pre- and post-operative populations. Additional higher-quality research is needed, particularly in the non-surgical population, including subgroup analyses of exercise type and setting.

Indexed as

exerciselung canceroverview of reviewsrehabilitation

Identifiers

PMID36902659
PMCPMC10003899

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read79
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.