Evidence map›Paper›PMID 36902635›Full record

ArticleJournal of clinical medicine2023

No Long-Term Mucosal Lesions in the Esophagus but More Gastric Mucosal Lesions after Sleeve Gastrectomy in Obese Rats.

Muriel Coupaye, Lara Ribeiro-Parenti, Clément Baratte, Muriel Hourseau, Alexandra Willemetz, Henri Duboc, Séverine Ledoux, André Bado, Anne Couvelard, Maude Le Gall

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In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muriel CoupayeUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.ORCID 0000-0002-8988-6260
Lara Ribeiro-ParentiUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.
Clément BaratteUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.
Muriel HourseauAssistance Publique-Hôpitaux de Paris, Service d'Anatomo-Pathologie, Hôpital Bichat-Claude-Bernard, 75018 Paris, France.
Alexandra WillemetzUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.
Henri DubocUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.ORCID 0000-0003-4359-7129
Séverine LedouxUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.
André BadoUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.ORCID 0000-0002-8007-1460
Anne CouvelardAssistance Publique-Hôpitaux de Paris, Service d'Anatomo-Pathologie, Hôpital Bichat-Claude-Bernard, 75018 Paris, France.
Maude Le GallUMRS 1149 Centre de Recherche sur l'Inflammation, Université Paris Cité, Inserm, 75018 Paris, France.ORCID 0000-0002-5372-4585

Funding

Fondation de l'Avenir AP-RM-19-002
6 · The paper itself

Abstract

Sleeve gastrectomy (SG) often induces gastroesophageal reflux, with few and discordant long-term data on the risk of Barrett's esophagus (BE) in operated patients. The aim of this study was to analyze the impact of SG on esogastric mucosa in a rat model at 24 weeks postoperatively, which corresponds to approximately 18 years in humans. After 3 months of a high-fat diet, obese male Wistar rats were subjected to SG (n = 7) or sham surgery (n = 9). Esophageal and gastric bile acid (BA) concentrations were measured at sacrifice, at 24 weeks postoperatively. Esophageal and gastric tissues were analyzed by routine histology. The esophageal mucosa of the SG rats (n = 6) was not significantly different in comparison to that of the sham rats (n = 8), with no esophagitis or BE. However, there was more antral and fundic foveolar hyperplasia in the mucosa of the residual stomach 24 weeks after SG than in the sham group (

Indexed as

bariatric surgeryBarrett’s esophagusesogastric mucosagastroesophageal reflux diseaseobesityratssleeve gastrectomy

Identifiers

PMID36902635
PMCPMC10003321

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read33
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.