ArticleJournal of clinical medicine2023
A Retrospective Analysis of the American Thrombosis and Hemostasis Network Dataset Describing Outcomes of Dental Extractions in Persons with Hemophilia.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Factors associated with postextraction bleeding in patients with hemophilia: a multicenter retrospective cohort study.Research and practice in thrombosis and haemostasis · 2026Article
- Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre.Haemophilia : the official journal of the World Federation of Hemophilia · 2025Article
- A literature review of major surgery experience with emicizumab in people with hemophilia A without factor VIII inhibitors.Research and practice in thrombosis and haemostasis · 2025Review
- Dental Considerations in Children with Inherited Bleeding Disorders and Inhibitors: A Systematic Review.Journal of clinical medicine · 2024Review
- Assessment of jaw bone mineral density, resorption rates, and oral health in patients with severe hemophilia: a case-control study.Acta odontologica Scandinavica · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
introductiondental extractions (DEs) in persons with hemophilia A or B (PWH-A or PWH-B) are often associated with bleeding and needing hemostatic therapies (HTs).
aimto analyze the American Thrombosis and Hemostasis Network (ATHN) dataset (ATHNdataset) to assess trends, uses and impacts of HT on bleeding outcomes following DEs.
methodsPWH seen at ATHN affiliates who underwent DEs and opted to share their data with the ATHNdataset between 2013-2019 were identified. The type of DEs, use of HT and bleeding outcomes were assessed.
resultsAmong 19,048 PWH ≥2 years of age, 1157 underwent 1301 episodes of DE. Those on prophylaxis experienced a nonsignificant reduction in dental bleeding episodes. Standard half-life factor concentrates were used more often than extended half-life products. PWHA were more likely to undergo DE in the first 30 years of life. Those with severe hemophilia were less likely to undergo DE than those with a mild disease (OR: 0.83; 95% CI: 0.72-0.95). PWH with inhibitors had statistically significantly increased odds of dental bleeding (OR: 2.09, 95% CI; 1.21-3.63).
conclusionour study showed that persons with mild hemophilia and younger age were more likely to undergo DE; the presence of inhibitors increased the likelihood of bleeding, while those with prophylaxis and receiving HT experienced a non-statistically significant reduction in bleeding.
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