Evidence map›Paper›PMID 36902611›Full record

ArticleJournal of clinical medicine2023

Combined LTP Sublingual and Oral Immunotherapy in LTP Syndrome: Efficacy and Safety.

Maria Aranzazu Martin Iglesias, Rosa Garcia Rodriguez, Alberto Palacios Cañas, Jaime Vinicio Meneses Sotomayor, Miriam Clar Castello, Francisco Feo Brito

Full text read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pollen-Food Allergy Syndrome in China: Current Knowledge and Future Research Needs.International archives of allergy and immunology · 2026
    Review
  2. IgE-mediated lipid transfer protein allergy in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Aranzazu Martin IglesiasAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.ORCID 0000-0002-4543-3745
Rosa Garcia RodriguezAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.
Alberto Palacios CañasAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.
Jaime Vinicio Meneses SotomayorAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.
Miriam Clar CastelloAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.
Francisco Feo BritoAllergy Department, General University Hospital of Ciudad Real, 13005 Ciudad Real, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSLIT for the treatment of plant food allergies has been demonstrated to be safe but less effective than OIT, but the latter is associated with more adverse reactions. The aim of the study was to evaluate the efficacy and safety of a new protocol starting with SLIT-peach followed by OIT with commercial peach juice in patients with LTP syndrome.

methodsThis was a prospective, noncontrolled, open study on patients with LTP syndrome who are not sensitized to storage proteins. SLIT peach ALK was followed by OIT with Granini

resultsForty-five patients were included, most of them with LTP anaphylaxis. Peach SLIT was well tolerated in 80.5%, and OIT with Granini

conclusionsThis combination of peach SLIT and OIT with commercial peach juice provides a new, fast, effective, and safe immunotherapy option for selected patients with LTP syndrome who are not allergic to storage proteins, improving their quality of life. This study suggests that cross-desensitization relative to the nsLTPs of several plant foods can be achieved by using Prup3.

Indexed as

FAQLQ-AFLTP desensitizationLTP lipid transfer proteinLTP syndromeoral immunotherapyquality of lifesublingual immunotherapy

Identifiers

PMID36902611
PMCPMC10003230

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.