Evidence map›Paper›PMID 36902608›Full record

ReviewJournal of clinical medicine2023

A Novel Insight into the Immune-Related Interaction of Inflammatory Cytokines in Benign Prostatic Hyperplasia.

Xiaokaiti Naiyila, Jinze Li, Yin Huang, Bo Chen, Mengli Zhu, Jin Li, Zeyu Chen, Lu Yang, Jianzhong Ai, Qiang Wei and 2 more

Registry-linked trialFull text readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07145034 (Evaluation Of Efficacy And Safety Of Prosman™), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07145034 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation Of Efficacy And Safety Of Prosman™ (Prunus Domestica Extract) On Prostate Function, Serum Testosterone Levels And Quality Of Life

TypeinterventionalSponsorAll India Institute of Medical Sciences, BhubaneswarRan2025 to 2026Enrolled38ConditionsHealthyArmsProsman, Placebo
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Review
  11. Mechanisms of prostatic inflammation-mediated male lower urinary tract symptoms.American journal of clinical and experimental urology · 2025
    Review
  12. Article
  13. Anti-Inflammatory Potential ofInternational journal of molecular sciences · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaokaiti NaiyilaDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jinze LiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Yin HuangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Bo ChenDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Mengli ZhuResearch Core Facility, West China Hospital, Sichuan University, Chengdu 610041, China.
Jin LiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Zeyu ChenDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Lu YangDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jianzhong AiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-0617-9286
Qiang WeiDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Liangren LiuDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
Dehong CaoDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

the National Natural Science Foundation of China 82000721
6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) is a common male condition that impacts many men's quality of life by generating lower urinary tract symptoms (LUTS). In recent years, inflammation has become very common in the prostate, and BPH with inflammation has a higher International Prostate Symptom Score (IPSS) score and an enlarged prostate. Chronic inflammation leads to tissue damage and the release of pro-inflammatory cytokines, which play an important role in the pathogenesis of BPH. We will focus on current advancements in pro-inflammatory cytokines in BPH, as well as the future of pro-inflammatory cytokine research.

Indexed as

agingbenign prostatic hyperplasiainflammationinflammatory factormicroenvironment

Identifiers

PMID36902608
PMCPMC10003138

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.