Evidence map›Paper›PMID 36902560›Full record

ArticleJournal of clinical medicine2023

Outcome of Kidney Transplants from Viremic and Non-Viremic Hepatitis C Virus Positive Donors into Negative Recipients: Results of the Spanish Registry.

Antonio Franco, Francesc Moreso, Eulàlia Solà-Porta, Isabel Beneyto, Núria Esforzado, Francisco Gonzalez-Roncero, Asunción Sancho, Edoardo Melilli, Juan Carlos Ruiz, Cristina Galeano and 1 more

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In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Assessing Tissue Transmission of Hepatitis C Virus From Viremic Donor to Seronegative Kidney Transplant Recipients: A Case Series.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonio FrancoNephrology Department, Hospital General Universitario, 03010 Alicante, Spain.
Francesc MoresoNephrology Department, Hospital Universitario Vall d'Hebron, Department of Medicine, Universitat Autònoma Barcelona, 08035 Barcelona, Spain.ORCID 0000-0002-7267-3963
Eulàlia Solà-PortaNephrology Department, Hospital del Mar-Parc de Salut Mar, 08003 Barcelona, Spain.
Isabel BeneytoNephrology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain.
Núria EsforzadoRenal Transplant Unit, Nephrology Department, Hospital Clínic, 08036 Barcelona, Spain.
Francisco Gonzalez-RonceroNephrology Department, Hospital Universitario Virgen del Rocío, 41013 Sevilla, Spain.ORCID 0000-0002-1944-8652
Asunción SanchoNephrology Department, Hospital Universitari Doctor Peset, 46017 Valencia, Spain.
Edoardo MelilliNephrology Department, Hospital Universitari Bellvitge, L'Hospitalet, 08907 Barcelona, Spain.ORCID 0000-0001-6965-3745
Juan Carlos RuizNephrology Department, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.
Cristina GaleanoNephrology Department, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.ORCID 0000-0003-2785-8886
Renal Transplantation with HCV Positive Donors Spanish Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, donor infection with hepatitis-C virus (HCV) has been a barrier to kidney transplantation. However, in recent years, it has been reported that HCV positive kidney donors transplanted into HCV negative recipients offer acceptable mid-term results. However, acceptance of HCV donors, especially viremic, has not broadened in the clinical practice. This is an observational, multicenter, retrospective study including kidney transplants from HCV positive donors into negative recipients reported to the Spanish group from 2013 to 2021. Recipients from viremic donors received peri-transplant treatment with direct antiviral agents (DAA) for 8-12 weeks. We included 75 recipients from 44 HCV non-viremic donors and 41 from 25 HCV viremic donors. Primary non function, delayed graft function, acute rejection rate, renal function at the end of follow up, and patient and graft survival were not different between groups. Viral replication was not detected in recipients from non-viremic donors. Recipient treatment with DAA started pre-transplant avoids (

Indexed as

graft outcomehepatitis C virushepatocellular carcinomakidney transplantationviremic donor

Identifiers

PMID36902560
PMCPMC10002558

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.