Evidence map›Paper›PMID 36902535›Full record

ArticleJournal of clinical medicine2023

The COVID-19 Vaccination Coverage in ICU Patients with Severe COVID-19 Infection in a Country with Low Vaccination Coverage-A National Retrospective Analysis.

Liana Valeanu, Stefan Andrei, Bianca Morosanu, Dan Longrois, Serban-Ion Bubenek-Turconi, Covati-Ro Collaborative

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liana ValeanuCardiac Anesthesiology and Intensive Care Department I, Emergency Institute for Cardiovascular Diseases C. C. Iliescu, 258 Fundeni Road, 022328 Bucharest, Romania.ORCID 0000-0001-7530-2781
Stefan AndreiAnesthesiology and Intensive Care Department, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Blvd., 050474 Bucharest, Romania.ORCID 0000-0002-0216-1380
Bianca MorosanuCardiac Anesthesiology and Intensive Care Department I, Emergency Institute for Cardiovascular Diseases C. C. Iliescu, 258 Fundeni Road, 022328 Bucharest, Romania.
Dan LongroisDepartment of Anesthesiology and Intensive Care, Bichat-Claude Bernard University Hospital, Sorbonne Universités, INSERM UMR 1148, 46 Rue Henri Huchard, 75018 Paris, France.
Serban-Ion Bubenek-TurconiCardiac Anesthesiology and Intensive Care Department I, Emergency Institute for Cardiovascular Diseases C. C. Iliescu, 258 Fundeni Road, 022328 Bucharest, Romania.
Covati-Ro Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRomania is one of the European countries with low COVID-19 vaccination coverage. The main goal of this study was to describe the COVID-19 vaccination status in patients admitted to Romanian ICUs with a severe COVID-19 infection. The study describes the patients' characteristics according to their vaccination status and evaluates the association between vaccination status and ICU mortality.

methodsThis retrospective, observational, multicenter study included patients with confirmed vaccination status admitted to Romanian ICUs from January 2021 to March 2022.

resultsTwo thousand, two hundred and twenty-two patients with confirmed vaccination status were included. Five point one three percent of patients were vaccinated with two vaccine doses and one point seventeen percent of patients were vaccinated with one vaccine dose. The vaccinated patients showed a higher rate of comorbidities but had similar clinical characteristics at ICU admission and lower mortality rates compared to non-vaccinated patients. Vaccinated status and higher Glasgow Coma Scale at ICU admission were independently associated with ICU survival. Ischemic heart disease, chronic kidney disease, higher SOFA score at ICU admission and the need for mechanical ventilation in ICU were independently associated with ICU mortality.

conclusionLower rates of ICU admission were observed in fully vaccinated patients even in a country with low vaccination coverage. The ICU mortality was lower for fully vaccinated patients compared to non-vaccinated patients. The benefit of vaccination on ICU survival could be more important in patients with associated comorbidities.

Indexed as

COVID-19ICUsurvivalvaccination

Identifiers

PMID36902535
PMCPMC10003614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.