ArticleJournal of clinical medicine2023
Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Labial Adhesion-An Uncommon Adult Condition: Clinical Features, Management and Histopathological Findings-A Case Series Study.Life (Basel, Switzerland) · 2026Article
- Case Report: Pelvic-perineal deep angiomyxoma presenting as hematoma-like paravaginal masses: a report of two cases.Frontiers in oncology · 2026Article
- Vulvar Aggressive Angiomyxoma in a Postmenopausal Woman: Diagnostic Pitfalls and Surgical Implications-A Case Report.Case reports in obstetrics and gynecology · 2026Article
- Aggressive clitoral angiomyxoma mimicking bartholinits: A case report and review of the literature.International journal of surgery case reports · 2025Article
- A Case Report of Aggressive Angiomyxoma in the Buttock of a Female.Clinical case reports · 2025Article
- Review
- Massive aggressive angiomyxoma of ischioanal region with relapse: A case report.International journal of reproductive biomedicine · 2024Article
- Aggressive Angiomyxoma of the Lower Female Genital Tract: A Review of the MITO Rare Tumors Group.Cancers · 2024Review
- Atypical Vaginal Aggressive Angiomyxoma in a Virgin: A Case Report from South Jordan.International journal of women's health · 2024Article
- Misleading clinical and imaging features in atypical aggressive angiomyxoma of the female vulvovaginal or perianal region: report of three cases and review of the literature.Frontiers in oncology · 2024Article
- Prepubertal Female Bartholin's Gland Abscess: A Comprehensive Case Report Study.Case reports in pediatrics · 2024Article
- Twisted aggressive angiomyxoma of the vulva presenting as an emergency with severe pain and impending gangrene.BMJ case reports · 2023Article
- Comprehensive next-generation sequencing reveals low-grade fibromyxoid sarcoma of the vulva missed by morphological diagnosis: a case report.Frontiers in medicine · 2023Article
- Superficial Angiomyxoma Revisited.In vivo (Athens, Greece)Review
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Authors and funding
6 authors.
Funding
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Abstract
backgroundAggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature.
methodsWe report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases.
resultsAggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up.
conclusionWide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.
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