Evidence map›Paper›PMID 36902401›Full record

ArticleInternational journal of molecular sciences2023

The Metagenomic Composition and Effects of Fecal-Microbe-Derived Extracellular Vesicles on Intestinal Permeability Depend on the Patient's Disease.

Cristina Rodríguez-Díaz, Flores Martín-Reyes, Bernard Taminiau, Ailec Ho-Plágaro, Raquel Camargo, Felix Fernandez-Garcia, José Pinazo-Bandera, Juan Pedro Toro-Ortiz, Montserrat Gonzalo, Carlos López-Gómez and 5 more

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Pharmacological Potential ofCurrent issues in molecular biology · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Extracellular Vesicles in Microbes, Pathogens, and Infectious Diseases.International journal of molecular sciences · 2023
    Article
  10. Membrane Vesicles of ToxigenicAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Cristina Rodríguez-DíazInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.
Flores Martín-ReyesInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.ORCID 0000-0002-3633-8367
Bernard TaminiauFundamental and Applied Research for Animals & Health (FARAH), Department of Food Microbiology, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, Belgium.ORCID 0000-0001-6456-329X
Ailec Ho-PlágaroInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.
Raquel CamargoUGC de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, 29010 Malaga, Spain.
Felix Fernandez-GarciaUGC de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, 29010 Malaga, Spain.
José Pinazo-BanderaUGC de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, 29010 Malaga, Spain.ORCID 0000-0002-8376-9573
Juan Pedro Toro-OrtizUGC de Aparato Digestivo, Hospital Universitario Virgen de la Victoria, 29010 Malaga, Spain.
Montserrat GonzaloUCG de Endocrinología y Nutrición, Hospital Regional Universitario, 29009 Malaga, Spain.
Carlos López-GómezInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.ORCID 0000-0003-2699-451X
Francisca Rodríguez-PachecoInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.
Dámaris Rodríguez de Los RíosInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.ORCID 0000-0001-7414-8524
Georges DaubeFundamental and Applied Research for Animals & Health (FARAH), Department of Food Microbiology, Faculty of Veterinary Medicine, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-9282-8408
Guillermo Alcain-MartinezInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.
Eduardo García-FuentesInstituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain.ORCID 0000-0002-3491-2724

Funding

Consejería de Salud y Familias PE-0098-2019Instituto de Salud Carlos III PI18/01652
6 · The paper itself

Abstract

The composition and impact of fecal-microbe-derived extracellular vesicles (EVs) present in different diseases has not been analyzed. We determined the metagenomic profiling of feces and fecal-microbe-derived EVs from healthy subjects and patients with different diseases (diarrhea, morbid obesity and Crohn's disease (CD)) and the effect of these fecal EVs on the cellular permeability of Caco-2 cells. The control group presented higher proportions of

Indexed as

Crohn DiseaseExtracellular VesiclesObesity, MorbidCaco-2 CellsDiarrheaFecesHumansdiarrheafecal-microbe-derived extracellular vesiclesinflammatory bowel diseaseintestinal permeabilitymetagenomemicrobiomemorbid obesity

Identifiers

PMID36902401
PMCPMC10002483

What OpenQuestion holds

Textfull text, public
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measurements read48
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.