Evidence map›Paper›PMID 36902387›Full record

ArticleInternational journal of molecular sciences2023

miRNome and Proteome Profiling of Human Keratinocytes and Adipose Derived Stem Cells Proposed miRNA-Mediated Regulations of Epidermal Growth Factor and Interleukin 1-Alpha.

Hady Shahin, Sallam Abdallah, Jyotirmoy Das, Weihai He, Ibrahim El-Serafi, Ingrid Steinvall, Folke Sjöberg, Moustafa Elmasry, Ahmed T El-Serafi

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Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hady ShahinDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.ORCID 0000-0003-3894-6849
Sallam AbdallahThe Department of Biomedical and Clinical Sciences, Linköping University, 58183 Linköping, Sweden.
Jyotirmoy DasBioinformatics, Core Facility, Division of Cell Biology, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, 58183 Linköping, Sweden.ORCID 0000-0002-5649-4658
Weihai HeThe Department of Biomedical and Clinical Sciences, Linköping University, 58183 Linköping, Sweden.
Ibrahim El-SerafiDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.ORCID 0000-0002-0463-1518
Ingrid SteinvallDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.
Folke SjöbergDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.
Moustafa ElmasryDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.
Ahmed T El-SerafiDepartment of Hand Surgery, Plastic Surgery and Burns, Linköping University, 58185 Linköping, Sweden.

Funding

Centre for Advanced Medical Products, Sweden 000000
6 · The paper itself

Abstract

Wound healing is regulated by complex crosstalk between keratinocytes and other cell types, including stem cells. In this study, a 7-day direct co-culture model of human keratinocytes and adipose-derived stem cells (ADSCs) was proposed to study the interaction between the two cell types, in order to identify regulators of ADSCs differentiation toward the epidermal lineage. As major mediators of cell communication, miRNome and proteome profiles in cell lysates of cultured human keratinocytes and ADSCs were explored through experimental and computational analyses. GeneChip

Indexed as

MicroRNAsEpidermal Growth FactorHumansInterleukin-1KeratinocytesProteomeStem CellsEpidermal Growth FactorInterleukin-1MicroRNAsMIRN485 microRNA, humanProteomeadipose-derived stem cellsdirect co-cultureepidermal growth factorinterleukin 1 alphakeratinocytesmiRNAproteomestem cell differentiation

Identifiers

PMID36902387
PMCPMC10002856

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read67
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.