Evidence map›Paper›PMID 36902270›Full record

ArticleInternational journal of molecular sciences2023

Aptamers as Novel Binding Molecules on an Antimicrobial Peptide-Armored Composite Hydrogel Wound Dressing for Specific Removal and Efficient Eradication of

Markus Kraemer, Magali Bellion, Ann-Kathrin Kissmann, Tilmann Herberger, Christopher V Synatschke, Anil Bozdogan, Jakob Andersson, Armando Rodriguez, Ludger Ständker, Sebastien Wiese and 7 more

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Application of Antimicrobial Peptides in Wound Dressings.Drug design, development and therapy · 2025
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Markus KraemerInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Magali BellionInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Tilmann HerbergerMax-Planck-Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Christopher V SynatschkeMax-Planck-Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.ORCID 0000-0002-4259-6696
Anil BozdoganCenter for Electrochemical Surface Technology (CEST), Austrian Institute of Technology, 3420 Tulln, Austria.
Jakob AnderssonAustrian Institute of Technology, Giefinggasse 4, 1210 Vienna, Austria.
Armando RodriguezCore Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ludger StändkerCore Unit of Mass Spectrometry and Proteomics, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Sebastien WieseCore Unit of Mass Spectrometry and Proteomics, Faculty of Medicine, Ulm University, 89081 Ulm, Germany.
Steffen StengerInstitute for Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany.
Barbara SpellerbergInstitute for Medical Microbiology and Hygiene, University Hospital Ulm, 89081 Ulm, Germany.
Kay-Eberhard GottschalkInstitute of Experimental Physics, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Ahmet CetinkayaInstitute of Polymer and Dye Technology, Lodz University of Technology, Stefanowskiego 16, 90-537 Lodz, Poland.ORCID 0000-0001-5280-3874
Joanna PietrasikInstitute of Polymer and Dye Technology, Lodz University of Technology, Stefanowskiego 16, 90-537 Lodz, Poland.ORCID 0000-0001-7438-9627
Tanja WeilMax-Planck-Institute for Polymer Research Mainz, Ackermannweg 10, 55128 Mainz, Germany.
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419

Funding

Alexander von Humboldt Foundation 1160914Baden-Württemberg Stiftung BiofMO_005 and MIKROBIOM: ID23 AMDADeutsche Forschungsgemeinschaft 465229237 and CRC1279Federal Ministry of Education and Research BMBF-WTZ-DLR, Germany Cuba, 2018-2020; BMBF/DLR 01DN18009German Academic Exchange Service 57592717Horizon 2020 686271National Science Centre, Poland UMO-2020/39/I/ST5/02108
6 · The paper itself

Abstract

Here we present for the first time a potential wound dressing material implementing aptamers as binding entities to remove pathogenic cells from newly contaminated surfaces of wound matrix-mimicking collagen gels. The model pathogen in this study was the Gram-negative opportunistic bacterium

Indexed as

HydrogelsWound InfectionAnti-Bacterial AgentsAntimicrobial PeptidesBandagesHumansPseudomonas aeruginosaAnti-Bacterial AgentsAntimicrobial PeptidesHydrogelsantimicrobial peptideaptamerfocused librarynext-generation wound dressing

Identifiers

PMID36902270
PMCPMC10002764

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read35
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.