Evidence map›Paper›PMID 36902170›Full record

ReviewInternational journal of molecular sciences2023

DNA Damage and Its Role in Cancer Therapeutics.

Jaeyoung Moon, Ichiwa Kitty, Kusuma Renata, Sisi Qin, Fei Zhao, Wootae Kim

Open access · goldFull text readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  7. TPI and GAPDH Interact with Rad9, Linking Glycolytic Enzymes to Cancer.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Jaeyoung MoonDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Ichiwa KittyDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Kusuma RenataDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Sisi QinDepartment of Pathology, University of Chicago, Chicago, IL 60637, USA.
Fei ZhaoCollege of Biology, Hunan University, Changsha 410082, China.
Wootae KimDepartment of Integrated Biomedical Science, Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan 31151, Chungcheongnam-do, Republic of Korea.ORCID 0000-0003-4364-3260
Soonchunhyang University · KRAtma Jaya Catholic University of Indonesia · IDHunan University · CNUniversity of Chicago · US

Funding

National Research Foundation of Korea NRF- 2019M3E5D3073092National Research Foundation of Korea NRF- 2019R1A5A8083404National Research Foundation of Korea NRF-2022R1A2C1091563
6 · The paper itself

Abstract

DNA damage is a double-edged sword in cancer cells. On the one hand, DNA damage exacerbates gene mutation frequency and cancer risk. Mutations in key DNA repair genes, such as breast cancer 1 (

Indexed as

DNA DamageDNA RepairNeoplasmsBRCA1 ProteinBRCA2 ProteinHumansMutationBRCA1 ProteinBRCA2 Proteincancer therapeuticsDNA damagemutations

Identifiers

PMID36902170
PMCPMC10003233
OpenAlexW4322742414

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.