Evidence map›Paper›PMID 36902109›Full record

ArticleInternational journal of molecular sciences2023

κ-Selenocarrageenan Oligosaccharides Prepared by Deep-Sea Enzyme Alleviate Inflammatory Responses and Modulate Gut Microbiota in Ulcerative Colitis Mice.

Kai Wang, Ling Qin, Junhan Cao, Liping Zhang, Ming Liu, Changfeng Qu, Jinlai Miao

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Frontiers in pharmacology · 2024
    Article
  7. Protective effect of carbon dots derived from scrambledFrontiers in molecular biosciences · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kai WangKey Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Ling QinKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.
Junhan CaoKey Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Liping ZhangKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.
Ming LiuKey Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Changfeng QuKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.
Jinlai MiaoKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.
Ministry of Natural Resources · CNOcean University of China · CNQingdao National Laboratory for Marine Science and Technology · CNFirst Institute of Oceanography · CN

Funding

Biosafety Research Program 20SWAQX04Key Research and Development Program of Shandong Province 2021TZXD008National Natural Science Foundation of China 32000074, 42176130Natural Science Foundation of Shandong Province ZR2021MD044Science and Technology Planning Project of Guangxi AA21196002Shandong Program of Qingdao Pilot National Laboratory for Marine Science and Technology 2022QNLM030003-1Tai Mountain Industry Leading Talent of Shandong 2019TSCYCX-06the Basic Scientific Fund for National Public Research Institutes of China 2022Q10, 2020Q02
6 · The paper itself

Abstract

κ-Selenocarrageenan (KSC) is an organic selenium (Se) polysaccharide. There has been no report of an enzyme that can degrade κ-selenocarrageenan to κ-selenocarrageenan oligosaccharides (KSCOs). This study explored an enzyme, κ-selenocarrageenase (SeCar), from deep-sea bacteria and produced heterologously in

Indexed as

CarrageenanColitis, UlcerativeGastrointestinal MicrobiomeOrganoselenium CompoundsAnimalsDextran SulfateDisease Models, AnimalInterleukin-6MiceMice, Inbred C57BLOligosaccharidesTumor Necrosis Factor-alphaCarrageenanDextran SulfateInterleukin-6kappa-selenocarrageenanOligosaccharidesOrganoselenium CompoundsTumor Necrosis Factor-alphaenzymatic preparationgut microbiotaheterologous expressionstructural characterizationulcerative colitisκ-selenocarrageenan oligosaccharides

Identifiers

PMID36902109
PMCPMC10003262
OpenAlexW4322628152

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read2
measurements read67
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.