ReviewInternational journal of molecular sciences2023
Cryopreservation of Human Spermatozoa: Functional, Molecular and Clinical Aspects.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.Journal of molecular medicine (Berlin, Germany) · 2026Pooled it
- The role and implication of platelet-rich plasma in male factor infertility: A systematic review of human studies.Andrology · 2026Pooled it
- Fresh versus frozen-thawed testicular sperm for intracytoplasmic sperm injection in men with non-obstructive azoospermia: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2026Review
- Recent Advances in Cryopreservation of Animal Genetic Resources: Principles, Influencing Factors, and Material-Specific Challenges.Animals : an open access journal from MDPI · 2026Review
- Sperm DNA fragmentation and its influence on mammalian reproduction.Nature reviews. Urology · 2026Review
- Optimize human sperm cryopreservation: influence of vial sealing methods and automated freezing protocols on preserved sperm quality.Translational andrology and urology · 2026Article
- The effect of zinc selenide nanospheres on porcine semen cryopreservation.Animal bioscience · 2026Article
- Long-term cryostorage does not impair human sperm motility: evidence from a three-decade cohort study.Journal of assisted reproduction and genetics · 2026Article
- Rescue of ICSI failure in non-obstructive azoospermia by switching from cryopreserved to fresh testicular sperm: a paired clinical analysis.Scientific reports · 2026Article
- Recovery of high-quality sperm after cryopreservation in the common marmoset (Callithrix jacchus)†.Biology of reproduction · 2026Article
- Protective Effect ofAntioxidants (Basel, Switzerland) · 2026Article
- Effects of the Freezing Diluent Tonicity and Prefreezing Cooling Rates on Post-Thaw Sperm Quality Markers in the Pure-Bred Arabian Stallion.Veterinary medicine international · 2026Article
- Cryopreservation increases sperm DNA fragmentation in normozoospermic Libyan men: the role of oxidative stress and the protective effect of melatonin.The Libyan journal of medicine · 2025Article
- Distinct post-insemination dynamics between fresh and frozen-derived gametes using testicular sperm.Journal of assisted reproduction and genetics · 2025Article
- Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction.Andrology · 2025Article
- The addition of heat shock protein 70 toOpen veterinary journal · 2025Article
- A novel small droplets freezing method for human sperm cryopreservation: maximizing utilization of limited samples.Journal of assisted reproduction and genetics · 2025Article
- Development of an improved medium for the preservation of human spermatozoa.Journal of assisted reproduction and genetics · 2025Article
- Silymarin as a promising antioxidant for sperm cryopreservation: a narrative review.Translational andrology and urology · 2025Review
- Fertility Preservation in More than 7000 Male Patients: A Single-Center, Tertiary Care Registry Study over 30 Years.Cancers · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Cryopreservation is an expanding strategy to allow not only fertility preservation for individuals who need such procedures because of gonadotoxic treatments, active duty in dangerous occupations or social reasons and gamete donation for couples where conception is denied, but also for animal breeding and preservation of endangered animal species. Despite the improvement in semen cryopreservation techniques and the worldwide expansion of semen banks, damage to spermatozoa and the consequent impairment of its functions still remain unsolved problems, conditioning the choice of the technique in assisted reproduction procedures. Although many studies have attempted to find solutions to limit sperm damage following cryopreservation and identify possible markers of damage susceptibility, active research in this field is still required in order to optimize the process. Here, we review the available evidence regarding structural, molecular and functional damage occurring in cryopreserved human spermatozoa and the possible strategies to prevent it and optimize the procedures. Finally, we review the results on assisted reproduction technique (ARTs) outcomes following the use of cryopreserved spermatozoa.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.