Evidence map›Paper›PMID 36902032›Full record

ReviewInternational journal of molecular sciences2023

Emerging RNA-Based Therapeutic and Diagnostic Options: Recent Advances and Future Challenges in Genitourinary Cancers.

Fabiana Tortora, Evelina La Civita, Pankaj Trivedi, Ferdinando Febbraio, Daniela Terracciano, Amelia Cimmino

Full text readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabiana TortoraInstitute of Genetics and Biophysics "A. Buzzati Traverso", National Research Council (CNR), 80131 Naples, Italy.ORCID 0000-0002-7594-102X
Evelina La CivitaDepartment of Translational Medical Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-0543-9031
Pankaj TrivediDepartment of Experimental Medicine, La Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0001-9574-6304
Ferdinando FebbraioInstitute of Biochemistry and Cell Biology, National Research Council (CNR), 80131 Naples, Italy.ORCID 0000-0002-3653-9847
Daniela TerraccianoDepartment of Translational Medical Sciences, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-4296-429X
Amelia CimminoInstitute of Genetics and Biophysics "A. Buzzati Traverso", National Research Council (CNR), 80131 Naples, Italy.ORCID 0000-0002-0004-9299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma, bladder cancer, and prostate cancer are the most widespread genitourinary tumors. Their treatment and diagnosis have significantly evolved over recent years, due to an increasing understanding of oncogenic factors and the molecular mechanisms involved. Using sophisticated genome sequencing technologies, the non-coding RNAs, such as microRNAs, long non-coding RNAs, and circular RNAs, have all been implicated in the occurrence and progression of genitourinary cancers. Interestingly, DNA, protein, and RNA interactions with lncRNAs and other biological macromolecules drive some of these cancer phenotypes. Studies on the molecular mechanisms of lncRNAs have identified new functional markers that could be potentially useful as biomarkers for effective diagnosis and/or as targets for therapeutic intervention. This review focuses on the mechanisms underlying abnormal lncRNA expression in genitourinary tumors and discusses their role in diagnostics, prognosis, and treatment.

Indexed as

Kidney NeoplasmsProstatic NeoplasmsRNA, Long NoncodingUrinary Bladder NeoplasmsBiomarkers, TumorHumansMaleBiomarkers, TumorRNA, Long Noncodingbladder cancergenitourinary cancerlong non-coding RNAmolecular biomarkersprostate cancerrenal cell carcinoma

Identifiers

PMID36902032
PMCPMC10003365

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read24
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.