Evidence map›Paper›PMID 36902013›Full record

ReviewInternational journal of molecular sciences2023

Pyodermitis during Nivolumab Treatment for Non-Small Cell Lung Cancer: A Case Report and Review of the Literature.

Terenzio Cosio, Filadelfo Coniglione, Valeria Flaminio, Roberta Gaziano, Deborah Coletta, Rosalba Petruccelli, Emi Dika, Luca Bianchi, Elena Campione

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In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Crossing the Barrier:Microorganisms · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Terenzio CosioDepartment of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-4025-7882
Filadelfo ConiglioneDepartment of Surgical Sciences, University Nostra Signora del Buon Consiglio, 1000 Tirana, Albania.
Valeria FlaminioMedical Oncology Unit, University of Rome Tor Vergata, Viale Oxford, 81, 00133 Rome, Italy.ORCID 0000-0002-2446-127X
Roberta GazianoDepartment of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1970-2670
Deborah ColettaMedical Oncology Unit, University of Rome Tor Vergata, Viale Oxford, 81, 00133 Rome, Italy.
Rosalba PetruccelliLaboratory of Microbiology, Microbiology and Virology Lab, Tor Vergata University Hospital, V. le Oxford, 81, 00133 Rome, Italy.
Emi DikaMelanoma Center, Dermatology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40126 Bologna, Italy.ORCID 0000-0003-3186-2861
Luca BianchiDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Viale Oxford, 81, 00133 Rome, Italy.ORCID 0000-0001-8697-6896
Elena CampioneDermatologic Unit, Department of Systems Medicine, University of Rome Tor Vergata, Viale Oxford, 81, 00133 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy in oncology is replacing traditional therapies due to it specific action and limited side effects. Despite the high efficacy of immunotherapy, side effects such as bacterial infection have been reported. Bacterial skin and soft tissue infections represent one of the most important differential diagnoses in patients presenting with reddened and swollen skin and soft tissue. Among these infections, cellulitis (phlegmon) and abscesses are the most frequent. In most cases, these infections occur locally with possible contiguous spread, or as a multifocal manifestation, especially in immunocompromised patients. Herein, we report a case of pyodermitis in an immunocompromised district in a patient treated with nivolumab for non-small cell lung cancer. A 64-year-old, smoker male patient showed cutaneous lesions at a different evolution level in the left arm, all in a tattooed area, with one phlegmon and two ulcerated lesions. Microbiological cultures and gram staining revealed an infection caused by a methicillin-susceptible but erythromycin-resistant (ER-R), clindamycin-resistant (CL-R), and gentamicin-resistant (GE-R)

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsStaphylococcal InfectionsAnti-Bacterial AgentsCellulitisHumansMaleMiddle AgedNivolumabAnti-Bacterial AgentsNivolumabcutaneous infectionimmunotherapynivolumabStaphylococcus aureus

Identifiers

PMID36902013
PMCPMC10003408

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.