Evidence map›Paper›PMID 36902006›Full record

ArticleInternational journal of molecular sciences2023

Machilin D Promotes Apoptosis and Autophagy, and Inhibits Necroptosis in Human Oral Squamous Cell Carcinoma Cells.

Hyung-Mun Yun, Yoon-Ju Kwon, Eonmi Kim, Hea-Jong Chung, Kyung-Ran Park

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Autophagy in oral cancer: Promises and challenges (Review).International journal of molecular medicine · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyung-Mun YunDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0001-6504-1610
Yoon-Ju KwonNational Development Institute for Korean Medicine, Gyeongsan 38540, Republic of Korea.
Eonmi KimNational Development Institute for Korean Medicine, Gyeongsan 38540, Republic of Korea.
Hea-Jong ChungGwangju Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea.ORCID 0000-0002-1185-7654
Kyung-Ran ParkGwangju Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea.

Funding

National Research Foundation of Korea 2022R1C1C1003491
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) accounts for about 90% of all head and neck cancers, the prognosis is very poor, and there are no effective targeted therapies. Herein, we isolated Machilin D (Mach), a lignin, from the roots of

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsApoptosisAutophagyCell Line, TumorCell ProliferationHumansLignansNecroptosisPhosphatidylinositol 3-KinasesSquamous Cell Carcinoma of Head and NeckLignansmachilin DPhosphatidylinositol 3-KinasesapoptosisautophagyMachilin DnecroptosisOSCC

Identifiers

PMID36902006
PMCPMC10002565

What OpenQuestion holds

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measurements read39
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.