Evidence map›Paper›PMID 36901935›Full record

ArticleInternational journal of molecular sciences2023

Semilicoisoflavone B Induces Apoptosis of Oral Cancer Cells by Inducing ROS Production and Downregulating MAPK and Ras/Raf/MEK Signaling.

Ming-Ju Hsieh, Hsin-Yu Ho, Yu-Sheng Lo, Chia-Chieh Lin, Yi-Ching Chuang, Mosleh Mohammad Abomughaid, Ming-Chang Hsieh, Mu-Kuan Chen

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In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ming-Ju HsiehOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0001-9726-3234
Hsin-Yu HoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-8496-1313
Yu-Sheng LoOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Chia-Chieh LinOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.ORCID 0000-0002-2746-4054
Yi-Ching ChuangOral Cancer Research Center, Changhua Christian Hospital, Changhua 500, Taiwan.
Mosleh Mohammad AbomughaidDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha 61922, Saudi Arabia.ORCID 0000-0001-9663-8874
Ming-Chang HsiehSchool of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung 40201, Taiwan.
Mu-Kuan ChenDepartment of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 402, Taiwan.
National Chung Hsing University · TWChanghua Christian Hospital · TWChung Shan Medical University Hospital · TWUniversity of Bisha · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is the sixth most common type of cancer worldwide. Despite advancement in treatment, advanced-stage OSCC is associated with poor prognosis and high mortality. The present study aimed to investigate the anticancer activities of semilicoisoflavone B (SFB), which is a natural phenolic compound isolated from

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsApoptosisCell Line, TumorCell ProliferationFlavonoidsHumansMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesProto-Oncogene Proteins c-rafras ProteinsReactive Oxygen SpeciesFlavonoidsMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesProto-Oncogene Proteins c-rafras ProteinsReactive Oxygen Speciessemilicoisoflavone BMAPKoral squamous cell carcinomaRas/Raf/MEKROSsemilicoisoflavone Bsurvivin

Identifiers

PMID36901935
PMCPMC10003514
OpenAlexW4322501438

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.