Evidence map›Paper›PMID 36901904›Full record

ArticleInternational journal of molecular sciences2023

Intracellular Helix-Loop-Helix Domain Modulates Inactivation Kinetics of Mammalian TRPV5 and TRPV6 Channels.

Lisandra Flores-Aldama, Daniel Bustos, Deny Cabezas-Bratesco, Wendy Gonzalez, Sebastian E Brauchi

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Lisandra Flores-AldamaInstituto de Fisiología, Facultad de Medicina, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0000-0003-3823-2635
Daniel BustosCentro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca 3460000, Chile.ORCID 0000-0002-2136-2305
Deny Cabezas-BratescoInstituto de Fisiología, Facultad de Medicina, Universidad Austral de Chile, Valdivia 5110566, Chile.
Wendy GonzalezCenter for Bioinformatics and Molecular Simulations (CBSM), University of Talca, Talca 3460000, Chile.ORCID 0000-0002-7535-6883
Sebastian E BrauchiInstituto de Fisiología, Facultad de Medicina, Universidad Austral de Chile, Valdivia 5110566, Chile.ORCID 0000-0002-8494-9912
Austral University of Chile · CLCatholic University of the Maule · CLUniversity of Talca · CLUniversity of Wisconsin–Madison · US

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
NHLBI NIH HHS T32 HL007936
6 · The paper itself

Abstract

TRPV5 and TRPV6 are calcium-selective ion channels expressed at the apical membrane of epithelial cells. Important for systemic calcium (Ca

Indexed as

CalciumTRPV Cation ChannelsAnimalsCalcium ChannelsEpithelial CellsHelix-Loop-Helix MotifsHumansMammalsCalciumCalcium ChannelsTRPV Cation Channelsinactivationmolecular evolutionTRP channelsTRPV5TRPV6

Identifiers

PMID36901904
PMCPMC10003196
OpenAlexW4321787513

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read19
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.