Evidence map›Paper›PMID 36901881›Full record

ArticleInternational journal of molecular sciences2023

TERT Extra-Telomeric Roles: Antioxidant Activity and Mitochondrial Protection.

Jessica Marinaccio, Emanuela Micheli, Ion Udroiu, Michela Di Nottia, Rosalba Carrozzo, Nicolò Baranzini, Annalisa Grimaldi, Stefano Leone, Sandra Moreno, Maurizio Muzzi and 1 more

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  3. Article
  4. Hypertension (Dallas, Tex. : 1979) · 2026
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  5. The Establishment of Asian Black Bear (Animals : an open access journal from MDPI · 2026
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  9. Article
  10. Review
  11. Review
  12. Article
  13. Telomere Reprogramming and Cellular Metabolism: Is There a Link?International journal of molecular sciences · 2024
    Review
  14. Tumor biomarkers for diagnosis, prognosis and targeted therapy.Signal transduction and targeted therapy · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jessica MarinaccioDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.
Emanuela MicheliDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.ORCID 0000-0002-1045-2209
Ion UdroiuDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.
Michela Di NottiaUnit of Muscular and Neurodegenerative Disorders, Laboratory of Molecular Medicine, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Rosalba CarrozzoUnit of Muscular and Neurodegenerative Disorders, Laboratory of Molecular Medicine, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.ORCID 0000-0002-3327-4054
Nicolò BaranziniDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-6996-4797
Annalisa GrimaldiDepartment of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9258-7595
Stefano LeoneDepartment of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-6339-6397
Sandra MorenoDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.ORCID 0000-0002-1079-3222
Maurizio MuzziDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.
Antonella SguraDepartment of Science, University "ROMA TRE", 00146 Rome, Italy.
Roma Tre University · ITBambino Gesù Children's Hospital · ITUniversity of Insubria · ITSapienza University of Rome · IT

Funding

The Grant of Excellence Departments, MIUR-Italy
6 · The paper itself

Abstract

Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase holoenzyme, which adds telomeric DNA repeats on chromosome ends to counteract telomere shortening. In addition, there is evidence of TERT non-canonical functions, among which is an antioxidant role. In order to better investigate this role, we tested the response to X-rays and H

Indexed as

AntioxidantsTelomeraseHumansHydrogen PeroxideMitochondriaOxidative StressAntioxidantsHydrogen PeroxideTelomeraseTERT protein, humanelectron microscopymitochondrionoxidative responseprimary cell linestelomerase catalytic subunit

Identifiers

PMID36901881
PMCPMC10002448
OpenAlexW4321787927

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read65
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.