Evidence map›Paper›PMID 36901828›Full record

ArticleInternational journal of molecular sciences2023

Identifying Drug Candidates for COVID-19 with Large-Scale Drug Screening.

Yifei Wu, Scott D Pegan, David Crich, Lei Lou, Lauren Nicole Mullininx, Edward B Starling, Carson Booth, Andrew Edward Chishom, Kuan Y Chang, Zhong-Ru Xie

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In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yifei WuSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-3202-3368
Scott D PeganDivision of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, CA 92521, USA.ORCID 0000-0002-2958-5319
David CrichDepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USA.
Lei LouSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Lauren Nicole MullininxSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Edward B StarlingSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Carson BoothSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Andrew Edward ChishomSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Kuan Y ChangDepartment of Computer Science and Engineering, National Taiwan Ocean University, Keelung 202, Taiwan.ORCID 0000-0002-2262-5218
Zhong-Ru XieSchool of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, GA 30602, USA.ORCID 0000-0002-1539-5100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papain-like protease (PL

Indexed as

COVID-19Antiviral AgentsCOVID-19 Drug TreatmentDrug Evaluation, PreclinicalHumansMolecular Docking SimulationMolecular Dynamics SimulationPapainProtease InhibitorsSARS-CoV-2Antiviral AgentsPapainProtease InhibitorsCOVID-19drug discoveryMD simulationsPL proteasevirtual screening

Identifiers

PMID36901828
PMCPMC10002104

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.