ReviewInternational journal of molecular sciences2023
The Main Theories on the Pathogenesis of Endometriosis.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
192 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Alterations in Cellular Immunity in Patients With Endometriosis: Systematic Review and Meta-Analysis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Pooled it
- Low-FODMAP Diet for Gastrointestinal Symptoms in Endometriosis: A Systematic Review.Nutrients · 2026Pooled it
- Neutrophil-to-lymphocyte ratio and endometriosis: systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Endometriosis Support and Development of Digital Technology-Based Interventions: Systematic Review.JMIR human factors · 2025Pooled it
- Pooled it
- Association between endometriosis and gut microbiota: systematic review and meta-analysis.Frontiers in microbiology · 2025Pooled it
- Effectiveness of psychological interventions in endometriosis: a systematic review with meta-analysis.Frontiers in psychology · 2024Pooled it
- MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis.BMC women's health · 2025Trial
- p53-mediated epigenetic regulation in the pathogenesis of endometriosis.Epigenetics · 2026Review
- The Endocannabinoid System in Endometriosis-Associated Pain: Mechanisms, Molecular Targets, and Therapeutic Implications.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Cancer-associated mutations in endometriosis reframe a benign disease through molecular oncology.Molecular oncology · 2026Review
- Curcumin Alleviates Endometriosis in Sexually Mature Female Mice by Targeting PKA and Inhibiting De Novo Estrogen Synthesis.Biomedicines · 2026Article
- A Rare Mimicker: Renal Endometriosis and Its Diagnostic Pitfalls-Review of Reported Cases.Diagnostics (Basel, Switzerland) · 2026Review
- Recent insights in pathogenesis of endometriosis with focus on gut microbiota.Molecular biology reports · 2026Review
- Coexistence of endometriosis and human papilloma virus: A systematic review and meta-analysis.New microbes and new infections · 2026Review
- Self-Esteem in Women with Endometriosis: A Qualitative Study of Psychosocial Burden and Self-Esteem-Related Experiences.Healthcare (Basel, Switzerland) · 2026Article
- N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.Antioxidants (Basel, Switzerland) · 2026Review
- Targeting the Immune Network in Endometriosis: A Comprehensive Review of Pathogenesis, Immunomodulation, and Emerging Therapies.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Are We Missing the Bladder? Reflections on Endometriosis and IC/BPS.International urogynecology journal · 2026Article
- A prospective surgical evaluation of the coexistence of endometriosis and interstitial cystitis/bladder pain syndrome.Archives of gynecology and obstetrics · 2026Article
132 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a complex disease, which is defined by abnormal growth of endometrial tissue outside the uterus. It affects about 10% of women of reproductive age all over the world. Endometriosis causes symptoms that notably worsen patient's well-being-such as severe pelvic pain, dysfunction of the organs of pelvic cavity, infertility and secondary mental issues. The diagnosis of endometriosis is quite often delayed because of nonspecific manifestations. Since the disease was defined, several different pathogenetic pathways have been considered, including retrograde menstruation, benign metastasis, immune dysregulation, coelomic metaplasia, hormonal disbalance, involvement of stem cells and alterations in epigenetic regulation, but the true pathogenesis of endometriosis remains poorly understood. The knowledge of the exact mechanism of the origin and progression of this disease is significant for the appropriate treatment. Therefore, this review reports the main pathogenetic theories of endometriosis based on current studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.