Evidence map›Paper›PMID 36901500›Full record

ArticleInternational journal of environmental research and public health2023

Trends of Antidiabetic and Cardiovascular Diseases Medication Prescriptions in Type 2 Diabetes between 2005 and 2017-A German Longitudinal Study Based on Claims Data.

Batoul Safieddine, Florian Trachte, Stefanie Sperlich, Jelena Epping, Karin Lange, Siegfried Geyer

Open access · goldFull text read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Batoul SafieddineMedical Sociology Unit, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Florian TrachteAccident and Emergency Department, St. Vincenz Hospital, Am Busdorf 2, 33098 Paderborn, Germany.
Stefanie SperlichMedical Sociology Unit, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.ORCID 0000-0003-4903-7384
Jelena EppingMedical Sociology Unit, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Karin LangeMedical Psychology Unit, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.ORCID 0000-0002-3636-2025
Siegfried GeyerMedical Sociology Unit, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DESt. Vincenz-Krankenhaus Limburg · DE

Funding

The Ministry of Science and Culture of Lower Saxony 76202-19-1/18 (74ZN1810)
6 · The paper itself

Abstract

backgroundWith an attempt to understand possible mechanisms behind the severity-dependent development of type 2 diabetes (T2D) comorbidities, this study examines the trends of antidiabetic and cardiovascular diseases (CVD) medication prescriptions in individuals with T2D.

methodsThe study is based on claims data from a statutory health insurance provider in Lower Saxony, Germany. The period prevalence of antidiabetic and CVD medication prescriptions was examined for the periods 2005-2007, 2010-2012, and 2015-2017 in 240,241, 295,868, and 308,134 individuals with T2D, respectively. (Ordered) logistic regression analyses were applied to examine the effect of time period on the number and prevalence of prescribed medications. Analyses were stratified by gender and three age groups.

resultsThe number of prescribed medications per person has increased significantly for all examined subgroups. For the two younger age groups, insulin prescriptions decreased but those of non-insulin medications increased, while both increased significantly over time for the age group of 65+ years. Except for glycosides and antiarrhythmic medications, the predicted probabilities for CVD medications increased over the examined periods, with lipid-lowering agents demonstrating the highest increase.

conclusionsResults point towards an increase in medication prescriptions in T2D, which is in line with the evidence of the increase in most comorbidities indicating morbidity expansion. The increase in CVD medication prescriptions, especially lipid-lowering agents, could explain the specific development of severe and less severe T2D comorbidities observed in this population.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2AgedDrug PrescriptionsHumansHypoglycemic AgentsHypolipidemic AgentsLipidsLongitudinal StudiesHypoglycemic AgentsHypolipidemic AgentsLipidsclaims dataGermanymedication prescriptionsmorbidity expansiontype 2 diabetes

Identifiers

PMID36901500
PMCPMC10001865
OpenAlexW4323046013

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.