Evidence map›Paper›PMID 36901413›Full record

ArticleInternational journal of environmental research and public health2023

Prevalence of Polymorphism and Post-Training Expression of ACTN3 (R/X) and ACE (I/D) Genes in CrossFit Athletes.

Omar Peña-Vázquez, Liliana Aracely Enriquez-Del Castillo, Susana Aideé González-Chávez, Jaime Güereca-Arvizuo, Ramon Candia Lujan, Claudia Esther Carrasco Legleu, Natanael Cervantes Hernández, César Pacheco-Tena

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In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Omar Peña-VázquezFaculty of Physical Culture Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31125, Mexico.
Liliana Aracely Enriquez-Del CastilloFaculty of Physical Culture Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31125, Mexico.ORCID 0000-0001-6125-6526
Susana Aideé González-ChávezPABIOM Laboratory, Faculty of Medicine and Biomedical Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31109, Mexico.
Jaime Güereca-ArvizuoDepartment of Health Sciences, Multidisciplinary Division of Ciudad Universitaria, Autonomous University of Cd. Juárez, Ciudad Juárez 32310, Mexico.
Ramon Candia LujanFaculty of Physical Culture Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31125, Mexico.
Claudia Esther Carrasco LegleuFaculty of Physical Culture Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31125, Mexico.
Natanael Cervantes HernándezFaculty of Physical Culture Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31125, Mexico.
César Pacheco-TenaPABIOM Laboratory, Faculty of Medicine and Biomedical Sciences, Autonomous University of Chihuahua, Campus II, Circuito Universitario S/N, Chihuahua 31109, Mexico.ORCID 0000-0002-0793-8988
Autonomous University of Chihuahua · MXUniversidad Autónoma de Ciudad Juárez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCrossFit is known as a functional fitness training high-intensity exercise to improve physical performance. The most studied polymorphisms are the ACTN3 R577X gene, known for speed, power, and strength, and ACE I/D, related to endurance and strength. The present investigation analyzed the effects of training on ACTN3 and ACE gene expression in CrossFit athletes for 12 weeks.

methodsthe studies included 18 athletes from the Rx category, where ACTN3 (RR, RX, XX) and ACE (II, ID, DD) characterization of genotypes and tests of maximum strength (NSCA), power (T-Force), and aerobic endurance (Course Navette) were performed. The technique used was the reverse transcription-quantitative PCR real-time polymerase chain reaction (RT-qPCR) for the relative expression analysis.

resultsthe relative quantification (RQ) values for the ACTN3 gene increased their levels 2.3 times (

conclusionsthere is an overexpression of the ACTN3 and ACE genes due to the effect of training for 12 weeks. Additionally, the correlation of the expression of the ACTN3 (

Indexed as

ExercisePolymorphism, GeneticActininAthletesGenotypeHumansPeptidyl-Dipeptidase APrevalenceACE protein, humanActininACTN3 protein, humanPeptidyl-Dipeptidase Aalpha-actinin-3 humanangiotensin-converting enzymeblood gene expressiongenotypeheterozygotehomozygotemolecular biologyphysical fitnessphysiology of exercisereal-time polymerase chain reaction

Identifiers

PMID36901413
PMCPMC10001917
OpenAlexW4322774460

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.