ArticleInternational journal of environmental research and public health2023
Polypharmacy and the Change of Self-Rated Health in Community-Dwelling Older Adults.
Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Questions on Medicines, Alcohol, and Illicit Drug Interactions in the Finnish AddictionLink Online Service: A Descriptive Analysis.Nordisk alkohol- & narkotikatidskrift : NAT · 2026Article
- Deprescribing & its associated factors among middle & old-aged ambulatory patients with chronic disease (s): A hospital-based cross-sectional study.The Indian journal of medical research · 2025Article
- Impact of medication use on olfactory performance in older adults.Frontiers in public health · 2025Observational
- Impact of a Clinical Decision Support System on the Efficiency and Effectiveness of Performing Medication Reviews in Community Pharmacies: A Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2024Article
- Change of self-rated physical health predicts mortality in aging individuals: results of a population-based cohort study.Archives of public health = Archives belges de sante publique · 2024Article
- Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist's geriatric assessment.Scientific reports · 2024Article
- Exploring the Influence of Social Class and Sex on Self-Reported Health: Insights from a Representative Population-Based Study.Life (Basel, Switzerland) · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polypharmacy is associated with poorer self-rated health (SRH). However, whether polypharmacy has an impact on the SRH progression is unknown. This study investigates the association of polypharmacy with SRH change in 1428 participants of the Berlin Initiative Study aged 70 years and older over four years. Polypharmacy was defined as the intake of ≥5 medications. Descriptive statistics of SRH-change categories stratified by polypharmacy status were reported. The association of polypharmacy with being in SRH change categories was assessed using multinomial regression analysis. At baseline, mean age was 79.1 (6.1) years, 54.0% were females, and prevalence of polypharmacy was 47.1%. Participants with polypharmacy were older and had more comorbidities compared to those without polypharmacy. Over four years, five SRH-change categories were identified. After covariate adjustment, individuals with polypharmacy had higher odds of being in the stable moderate category (OR 3.55; 95% CI [2.43-5.20]), stable low category (OR 3.32; 95% CI [1.65-6.70]), decline category (OR 1.87; 95% CI [1.34-2.62]), and improvement category (OR 2.01; [1.33-3.05]) compared to being in the stable high category independent of the number of comorbidities. Reducing polypharmacy could be an impactful strategy to foster favorable SRH progression in old age.
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