Evidence map›Paper›PMID 36901028›Full record

Trial reportInternational journal of environmental research and public health2023

Negligible Effects of Nutraceuticals from Beetroot Extract on Cardiovascular and Autonomic Recovery Response following Submaximal Aerobic Exercise in Physically Active Healthy Males: A Randomized Trial.

Cicero Jonas R Benjamim, Francisco Welington de Sousa Júnior, Andrey Alves Porto, Camila Venancia Guerra Andrade, Maria Íris L Saraiva de Figueiredo, Cicera Josilânia R Benjamim, Guilherme da Silva Rodrigues, Elida M Braga Rocha, Taisy Ferro Cavalcante, David M Garner and 2 more

Open access · goldFull text readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Cicero Jonas R BenjamimDepartment of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.ORCID 0000-0002-8679-7166
Francisco Welington de Sousa JúniorUniversity Center of the Juazeiro do Norte, Juazeiro do Norte 63010-475, CE, Brazil.ORCID 0000-0002-7113-276X
Andrey Alves PortoSão Paulo State University (UNESP), Presidente Prudente, São Paulo Brazil; Autonomic Nervous System Center, UNESP, Marília 17525-900, São Paulo.ORCID 0000-0003-1097-5285
Camila Venancia Guerra AndradeDevelopment Nutrition, Phytotherapy and Hygiene Research Group, University of Pernambuco, Petrolina 56328-900, PE, Brazil.
Maria Íris L Saraiva de FigueiredoUniversity Center of the Juazeiro do Norte, Juazeiro do Norte 63010-475, CE, Brazil.
Cicera Josilânia R BenjamimUniversity Center of the Juazeiro do Norte, Juazeiro do Norte 63010-475, CE, Brazil.
Guilherme da Silva RodriguesDepartment of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.ORCID 0000-0002-9931-4709
Elida M Braga RochaUniversity Center of the Juazeiro do Norte, Juazeiro do Norte 63010-475, CE, Brazil.
Taisy Ferro CavalcanteDevelopment Nutrition, Phytotherapy and Hygiene Research Group, University of Pernambuco, Petrolina 56328-900, PE, Brazil.
David M GarnerSão Paulo State University (UNESP), Presidente Prudente, São Paulo Brazil; Autonomic Nervous System Center, UNESP, Marília 17525-900, São Paulo.ORCID 0000-0002-8114-9055
Vitor Engracia ValentiSão Paulo State University (UNESP), Presidente Prudente, São Paulo Brazil; Autonomic Nervous System Center, UNESP, Marília 17525-900, São Paulo.ORCID 0000-0001-7477-3805
Carlos R Bueno JúniorDepartment of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, SP, Brazil.ORCID 0000-0002-2228-0758
Universidade de São Paulo · BRCentro Universitário do Norte · BROxford Brookes University · GBUniversidade de Pernambuco · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is little evidence that nutraceuticals from beetroot extract are beneficial with regards to recovery of the cardiovascular parameters and the autonomic nervous system (ANS) after submaximal aerobic exercise, though this formulation is employed widely for this purpose.

objectiveTo study the effects of beetroot extract supplementation on the recovery of cardiorespiratory and autonomic parameters after a session of submaximal aerobic exercise.

methodsSixteen healthy male adults commenced a cross-over, randomized, double-blind and placebo-controlled trial. Beetroot extract (600 mg) or placebo (600 mg) were ingested 120 min prior to evaluation on randomized days. We assessed systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), mean arterial pressure (MAP), heart rate (HR) and HR variability (HRV) indexes at Rest and during 60 min of recovery from submaximal aerobic exercise.

resultsBeetroot extract ingestion slightly accelerated HR, SBP, DBP and MAP reduction following exercise associated to the placebo protocol (vs. rest). Yet no group effect (

conclusionWhilst beetroot extract might assist the recovery of the cardiovascular and autonomic systems following submaximal aerobic exercise in healthy males, these results seem insignificant owing to minor differences between interventions and are weak clinically.

Indexed as

Cardiovascular SystemAdultAutonomic Nervous SystemBlood PressureDietary SupplementsExerciseHeartHeart RateHumansMaleVegetablesautonomic nervous systemBeta vulgaris L.cardiovascular systemdietary supplementsexercise

Identifiers

PMID36901028
PMCPMC10002462
OpenAlexW4321787238

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read38
identifiers read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.