Trial reportInternational journal of environmental research and public health2023
Modulation of Heart Rate Variability following PAP Ion Magnetic Induction Intervention in Subjects with Chronic Musculoskeletal Pain: A Pilot Randomized Controlled Study.
Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Patient Satisfaction with Advanced Medical Technology-Based Treatments in Integrative Medicine: A Structural Equation Modeling Approach Among Patients with Chronic Diseases.Healthcare (Basel, Switzerland) · 2026Article
- PAPIMI Short Effect on Pain Perception and Heart Rate Variability in Chronic Musculoskeletal Pain: A Pilot Study.Healthcare (Basel, Switzerland) · 2025Article
- Percutaneous Electrolysis, Percutaneous Peripheral Nerve Stimulation, and Eccentric Exercise for Shoulder Pain and Functionality in Supraspinatus Tendinopathy: A Single-Blind Randomized Clinical Trial.Journal of functional morphology and kinesiology · 2025Article
- Pulsed Electromagnetic Field (PEMF) stimulation as an adjunct to exercise: a brief review.Frontiers in sports and active living · 2024Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart rate variability (HRV) analysis has emerged as a simple and non-invasive technique to indirectly evaluate the autonomic nervous system (ANS), and it is considered a sensible and advanced index of health status. Pulsed electromagnetic fields (PEMFs) are widely used in clinical settings for improving the health status of individuals with chronic musculoskeletal pain. The aim of the present single-blind, randomized, placebo-controlled parallel pilot study was to investigate the acute effect of a single session of PEMFs stimulation by a PAP ion magnetic induction (PAPIMI) device on ANS activity, as measured by HRV, in patients with chronic musculoskeletal pain, and compare such effect with that induced by a sham (control) PAPIMI inductor. Thirty-two patients were randomized into two groups: PAPIMI intervention (PAP) (n = 17) and sham PAPIMI intervention (SHAM-PAP) (n = 15). HRV was assessed before and following the interventions. The PAP group showed a significant increase in all values of the time-domain parameters (SDNN, RMSSD, NN50, and pNN50) and the HF component of HRV, suggesting a parasympathetic effect. In contrast, the SHAM-PAP group showed no significant differences in all HRV indices following the intervention. Preliminary findings suggested that PAPIMI inductor could influence ANS activity and provided initial evidence of the potential physiological response induced by the PAPIMI device.
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