Evidence map›Paper›PMID 36900863›Full record

ArticleInternational journal of environmental research and public health2023

Cost-Impact Analysis of a Novel Diagnostic Test to Assess Community-Acquired Pneumonia Etiology in the Emergency Department Setting: A Multi-Country European Study.

Hirad Houshmand, Camilla Porta, Lorenzo Pradelli, Matteo Pinciroli, Giovanni Sotgiu

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Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hirad HoushmandDiaSorin SpA, Via Crescentino, 13040 Saluggia, Italy.ORCID 0000-0001-5208-2499
Camilla PortaAdRes Health Economics and Outcomes Research, 10121 Torino, Italy.ORCID 0000-0001-8402-6934
Lorenzo PradelliAdRes Health Economics and Outcomes Research, 10121 Torino, Italy.
Matteo PinciroliDiaSorin SpA, Via Crescentino, 13040 Saluggia, Italy.
Giovanni SotgiuScienze Mediche Chirurgiche E Sperimentali, Università degli Studi di Sassari, 07100 Sassari, Italy.ORCID 0000-0002-1600-4474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to estimate the economic and clinical impacts of a novel diagnostic test called LIAISON

methodsA cost-impact simulation model was developed to investigate the financial consequences of the introduction of LMMBV into the standard of care (SOC) diagnostic process in Italy, Germany, and Spain. Clinical outcomes were expressed as antibiotic patients and days saved, reduced hospital admissions, and shortened hospital length of stay (LOS). Cost savings were evaluated from the perspectives of third-party payers and hospitals. A deterministic sensitivity analysis (DSA) was carried out.

resultsLMMBV was associated with a reduction in antibiotic prescriptions, treatment duration, and LOS. Furthermore, the adoption of LMMBV would allow savings per patient up to EUR 364 and EUR 328 for hospitals and EUR 91 and EUR 59 for payers in Italy and Germany, respectively. In Spain, average savings per patient could reach up to EUR 165 for both payers and hospitals. Savings were most sensitive to test accuracy, with DSA confirming the robustness of the results.

conclusionsCombining LMMBV with the current SOC diagnostic process is expected to provide clinical and economic benefits in Italy, Germany, and Spain.

Indexed as

Community-Acquired InfectionsPneumoniaAnti-Bacterial AgentsCosts and Cost AnalysisDiagnostic Tests, RoutineHospitalizationHumansAnti-Bacterial Agentscommunity-acquired pneumoniacost-impactdiagnostic testinghost-responselower respiratory tract infection

Identifiers

PMID36900863
PMCPMC10001249

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.