Evidence map›Paper›PMID 36900737›Full record

ArticleHealthcare (Basel, Switzerland)2023

Importance of Asprosin for Changes of M. Rectus Femoris Area during the Acute Phase of Medical Critical Illness: A Prospective Observational Study.

Hilal Sipahioglu, Hatice Kubra Zenger Ilik, Nurhayat Tugra Ozer, Sevda Onuk, Sumeyra Koyuncu, Sibel Kuzuguden, Gulseren Elay

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Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hilal SipahiogluDepartment of Intensive Care Unit, Kayseri City Training and Research Hospital, Kayseri 38080, Turkey.ORCID 0000-0002-7884-2094
Hatice Kubra Zenger IlikDepartment of Internal Medicine, Kayseri Training and Research Hospital, Kayseri 38080, Turkey.ORCID 0000-0002-7170-2064
Nurhayat Tugra OzerDepartment of Clinical Nutrition, Erciyes School of Medicine, Erciyes University, Kayseri 38080, Turkey.ORCID 0000-0002-8260-9295
Sevda OnukDepartment of Intensive Care Unit, Kayseri City Training and Research Hospital, Kayseri 38080, Turkey.ORCID 0000-0001-7601-1601
Sumeyra KoyuncuDepartment of Nephrology, Kayseri City Training and Research Hospital, Kayseri 38080, Turkey.
Sibel KuzugudenDepartment of Biochemistry, Kayseri City Training and Research Hospital, Kayseri 38080, Turkey.
Gulseren ElayDepartment of Intensive Care Unit, Gaziantep University, Gaziantep 27470, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asprosin, a new adipokine, is secreted by subcutaneous white adipose tissue and causes rapid glucose release. The skeletal muscle mass gradually diminishes with aging. The combination of decreased skeletal muscle mass and critical illness may cause poor clinical outcomes in critically ill older adults. To determine the relationship between the serum asprosin level, fat-free mass, and nutritional status of critically ill older adult patients, critically ill patients over the age of 65 receiving enteral nutrition via feeding tube were included in the study. The patients' cross-sectional area of the rectus femoris (RF) of the lower extremity quadriceps muscle was evaluated by serial measurements. The mean age of the patients was 72 ± 6 years. The median (IQR) serum asprosin level was 31.8 (27.4-38.1) ng/mL on the first study day and 26.1 (23.4-32.3) ng/mL on the fourth study day. Serum asprosin level was high in 96% of the patients on the first day, and it was high in 74% on the fourth day after initiation of enteral feeding. The patients achieved 65.9 ± 34.1% of the daily energy requirement for four study days. A significant moderate correlation between delta serum asprosin level and delta RF was found (Rho = -0.369,

Indexed as

adipokineasprosinICUmuscle massolder adult patients

Identifiers

PMID36900737
PMCPMC10000515

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.