Evidence map›Paper›PMID 36900437›Full record

ArticleFoods (Basel, Switzerland)2023

Fermented Wheat Germ Alleviates Depression-like Behavior in Rats with Chronic and Unpredictable Mild Stress.

Zheyuan Hu, Penghui Zhao, Aimei Liao, Long Pan, Jie Zhang, Yuqi Dong, Jihong Huang, Weiwei He, Xingqi Ou

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In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Foods (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheyuan HuSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Penghui ZhaoSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Aimei LiaoSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Long PanSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Jie ZhangSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Yuqi DongSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.
Jihong HuangSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.ORCID 0000-0002-0754-409X
Weiwei HeKey Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, Institute of Surface Micro and Nano Materials, College of Chemical and Materials Engineering, Xuchang University, Xuchang 461000, China.
Xingqi OuCollege of Life Science and Technology, Henan Institute of Science and Technology, Xinxiang 453003, China.

Funding

Innovation Demonstration Special Project of Henan Province (201111110100)Key Project Foundation of Natural Science Research of Universities of Henan Province in China (20A550004)Major Science and Technology Projects for Public Welfare of Henan Province (201300110300)the Program for Zhongyuan Leading Talents of Science and Technology Innovation in Henan Province (204200510016)Zhongyuan Scholars in Henan (No. 192101510004)
6 · The paper itself

Abstract

Depression is a chronic mental illness with devastating effects on a person's physical and mental health. Studies have reported that food fermentation with probiotics can enrich the nutritional values of food and produce functional microorganisms that can alleviate depression and anxiety. Wheat germ is an inexpensive raw material that is rich in bioactive ingredients. For example, gamma-aminobutyric acid (GABA) is reported to have antidepressant effects. Several studies concluded that

Indexed as

behaviordepressionFWGintestinal microbesneurotransmitters

Identifiers

PMID36900437
PMCPMC10000856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.