Evidence map›Paper›PMID 36900352›Full record

ArticleCancers2023

Myelotoxicity of Temozolomide Treatment in Patients with Glioblastoma Is It Time for a More Mechanistic Approach?

Medhat M Said, Martinus P G Broen, Eleonora L Swart, Imke H Bartelink, Mathilde C M Kouwenhoven

Full text readEditorial
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. CAR-neutrophils produced in vivo to treat glioma.Nature biomedical engineering · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Medhat M SaidDepartment of Pharmacy & Clinical Pharmacology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-7954-6580
Martinus P G BroenDepartment of Neurology, Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands.ORCID 0000-0002-8834-2202
Eleonora L SwartDepartment of Pharmacy & Clinical Pharmacology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-5138-7784
Imke H BartelinkDepartment of Pharmacy & Clinical Pharmacology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-9602-3407
Mathilde C M KouwenhovenCancer Treatment and Quality of Life, Cancer Center Amsterdam, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-5252-4365

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma multiforme is the most common primary central nervous system tumor, with an incidence of 3 [...].

Identifiers

PMID36900352
PMCPMC10000921

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read18
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.