Evidence map›Paper›PMID 36900277›Full record

ArticleCancers2023

Constitutive Expression of a Cytotoxic Anticancer Protein in Tumor-Colonizing Bacteria.

Phuong-Thu Mai, Daejin Lim, EunA So, Ha Young Kim, Taner Duysak, Thanh-Quang Tran, Miryoung Song, Jae-Ho Jeong, Hyon E Choy

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In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Genetic engineering ofEcoSal Plus · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phuong-Thu MaiDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.ORCID 0000-0002-2974-931X
Daejin LimDivision of Biomedical Convergence, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
EunA SoDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.ORCID 0000-0003-0019-1073
Ha Young KimDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.
Taner DuysakDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.ORCID 0000-0001-7603-0458
Thanh-Quang TranDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.
Miryoung SongDepartment of Bioscience and Biotechnology, Hankuk University of Foreign Studies, Yongin 17035, Republic of Korea.
Jae-Ho JeongDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.ORCID 0000-0002-5544-9572
Hyon E ChoyDepartment of Microbiology, Chonnam National University Medical School, Gwangju 61468, Republic of Korea.

Funding

Chonnam National University 2019-0232National Research Foundation of Korea 2020R1A5A2031185the Ministry of SMEs and Startups (MSS, Korea) S3130592
6 · The paper itself

Abstract

Bacterial cancer therapy is a promising next-generation modality to treat cancer that often uses tumor-colonizing bacteria to deliver cytotoxic anticancer proteins. However, the expression of cytotoxic anticancer proteins in bacteria that accumulate in the nontumoral reticuloendothelial system (RES), mainly the liver and spleen, is considered detrimental. This study examined the fate of the

Indexed as

anticancer protein expressionbacterial cancer therapyEscherichia colihost responseSalmonella enterica serovar Gallinarum

Identifiers

PMID36900277
PMCPMC10000871

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read44
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.