Evidence map›Paper›PMID 36900258›Full record

ArticleCancers2023

Aberrant Methylation of the Imprinted C19MC and MIR371-3 Clusters in Patients with Non-Small Cell Lung Cancer.

Laura Boyero, José Francisco Noguera-Uclés, Alejandro Castillo-Peña, Ana Salinas, Amparo Sánchez-Gastaldo, Miriam Alonso, Johana Cristina Benedetti, Reyes Bernabé-Caro, Luis Paz-Ares, Sonia Molina-Pinelo

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In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura BoyeroInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-2603-399X
José Francisco Noguera-UclésInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0003-4956-116X
Alejandro Castillo-PeñaInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.ORCID 0009-0000-8650-141X
Ana SalinasInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Amparo Sánchez-GastaldoInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Miriam AlonsoInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Johana Cristina BenedettiInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Reyes Bernabé-CaroInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.
Luis Paz-AresH12O Lung Cancer Clinical Research Unit, Health Research Institute Hospital 12 de Octubre (imas12), 28029 Madrid, Spain.
Sonia Molina-PineloInstitute of Biomedicine of Seville (IBiS), HUVR, CSIC, Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-5726-2453

Funding

Andalusian Research, Development and Innovation Plan PY20_00992Asociación Española Contra el Cáncer TRNSC18004PAZCentro de Investigación Biomédica en Red CD16/12/00442Instituto de Salud Carlos III AC20/0070Instituto de Salud Carlos III CM20/00178Instituto de Salud Carlos III F21/00226Instituto de Salud Carlos III PI20/00870Instituto de Salud Carlos III PI20/01109The Andalusian Research, Development and Innovation Plan PY20_00951The Ministry of Health and Social Welfare of the Junta de Andalucía PECART-0091-2020The Ministry of Health and Social Welfare of the Junta de Andalucía RC-0004-2020The Ministry of Health and Social Welfare of the Junta de Andalucía RH-0051-2020
6 · The paper itself

Abstract

Epigenetic mechanisms have emerged as an important contributor to tumor development through the modulation of gene expression. Our objective was to identify the methylation profile of the imprinted C19MC and MIR371-3 clusters in patients with non-small cell lung cancer (NSCLC) and to find their potential target genes, as well as to study their prognostic role. DNA methylation status was analyzed in a NSCLC patient cohort (

Indexed as

C19MC and MIR371-3 clustersDNA methylationmiRNA–target mRNA expressionnon-small cell lung cancer (NSCLC)prognosis

Identifiers

PMID36900258
PMCPMC10000578

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.