Evidence map›Paper›PMID 36899831›Full record

ArticleCells2023

Intrahippocampal Inoculation of Aβ

Ruth Aquino, Vidian de Concini, Marc Dhenain, Suzanne Lam, David Gosset, Laura Baquedano, Manuel G Forero, Arnaud Menuet, Patrick Baril, Chantal Pichon

Open access · goldFull text read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Comparative Study of Injected Alzheimer's Disease Models in Rats: Insights from Experimental Research.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ruth AquinoCentre de Biophysique Moléculaire, CNRS UPR 4301, Rue Charles Sadron CS 80054, CEDEX 02, 45071 Orléans, France.ORCID 0000-0001-7692-091X
Vidian de ConciniExperimental and Molecular Immunology and Neurogenetic, UMR7355 CNRS, 45071 Orléans, France.
Marc DhenainCEA, CNRS, Laboratoire des Maladies Neurodégénératives, Université Paris-Saclay, 18 Route du Panorama, 92265 Fontenay-aux-Roses, France.ORCID 0000-0001-8804-4101
Suzanne LamCEA, CNRS, Laboratoire des Maladies Neurodégénératives, Université Paris-Saclay, 18 Route du Panorama, 92265 Fontenay-aux-Roses, France.
David GossetCentre de Biophysique Moléculaire, CNRS UPR 4301, Rue Charles Sadron CS 80054, CEDEX 02, 45071 Orléans, France.ORCID 0000-0003-3143-0815
Laura BaquedanoFaculty of Science and Philosophy, Universidad Peruana Cayetano Heredia, Lima 4314, Peru.
Manuel G ForeroProfessional School of Systems Engineering, Faculty of Engineering, Architecture and Urban Planning, Universidad Señor de Sipán, Chiclayo 14000, Peru.ORCID 0000-0001-9972-8621
Arnaud MenuetFaculty of Science and Techniques, University of Orléans, 45067 Orléans, France.ORCID 0000-0001-9092-006X
Patrick BarilCentre de Biophysique Moléculaire, CNRS UPR 4301, Rue Charles Sadron CS 80054, CEDEX 02, 45071 Orléans, France.
Chantal PichonCentre de Biophysique Moléculaire, CNRS UPR 4301, Rue Charles Sadron CS 80054, CEDEX 02, 45071 Orléans, France.ORCID 0000-0003-3161-3937
Centre National de la Recherche Scientifique · FRUniversité d'Orléans · FRUniversidad Peruana Cayetano Heredia · PEUniversidad Señor de Sipán · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer's disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated Aβ

Indexed as

Alzheimer DiseaseMicroRNAsAmyloid beta-PeptidesAnimalsAnti-Inflammatory AgentsAstrocytesInterleukin-6MiceNF-kappa BPeptide FragmentsRatsAmyloid beta-Peptidesamyloid beta-protein (1-42)Anti-Inflammatory AgentsInterleukin-6MicroRNAsMIRN146a microRNA, ratNF-kappa BPeptide FragmentsAlzheimer’s diseaseAβ1–42 peptidebiomarkersdiagnosismicroRNAsmiRNA-146a-5p

Identifiers

PMID36899831
PMCPMC10000752
OpenAlexW4321500272

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read166
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.