ArticleAnimals : an open access journal from MDPI2023
Rumen-Protected Lysine and Methionine Supplementation Reduced Protein Requirement of Holstein Bulls by Altering Nitrogen Metabolism in Liver.
Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Effects of Replacing Alfalfa withAnimals : an open access journal from MDPI · 2026Article
- Effects of Rumen-Protected Methionine and Lysine on the Fecal Microbiota of Leizhou Goats.Microorganisms · 2025Article
- Effect of Rumen-Protected Lysine Supplementation on Growth Performance, Blood Metabolites, Rumen Fermentation and Bacterial Community on Feedlot Yaks Offered Corn-Based Diets.Animals : an open access journal from MDPI · 2025Article
- β-Alanine decreases plasma taurine but improves nitrogen utilization efficiency in beef steers.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Alterations in Methionine Cycle and Wnt/MAPK Signaling Associated with HMBi-Induced Cashmere Growth in Goats.International journal of molecular sciences · 2025Article
- Different lysine-to-methionine ratios in a low-protein diet affect the microbiome and metabolome, influencing the jejunal barrier function in Tibetan sheep.Frontiers in microbiology · 2025Article
- Integrated Transcriptomic Analyses of Liver and Mammary Gland Tissues Reveals the Regulatory Mechanism Underlying Dairy Goats at Late Lactation When Feeding Rumen-Protected Lysine.International journal of molecular sciences · 2024Article
- Effects of Dietary Protein Level and Rumen-Protected Methionine and Lysine on Growth Performance, Rumen Fermentation and Serum Indexes for Yaks.Animals : an open access journal from MDPI · 2024Article
- Effect of glucose and lysine supplementation on myogenic and adipogenic gene expression in muscle satellite cells isolated from Hanwoo with different genotypes of PLAG1: Implications for cell-based food production.Current research in food science · 2024Article
- Enhancing Metabolism and Milk Production Performance in Periparturient Dairy Cattle through Rumen-Protected Methionine and Choline Supplementation.Metabolites · 2023Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
The aim of this study was to investigate the effect of low-protein diets supplemented with rumen-protected lysine (RPLys) and methionine (RPMet) on growth performance, rumen fermentation, blood biochemical parameters, nitrogen metabolism, and gene expression related to N metabolism in the liver of Holstein bulls. Thirty-six healthy and disease-free Holstein bulls with a similar body weight (BW) (424 ± 15 kg, 13 months old) were selected. According to their BW, they were randomly divided into three groups with 12 bulls in each group in a completely randomized design. The control group (D1) was fed with a high-protein basal diet (CP13%), while bulls in two low-protein groups were supplied a diet with 11% crude protein and RPLys 34 g/d·head + RPMet 2 g/d·head (low protein with low RPAA, T2) or RPLys 55 g/d·head + RPMet 9 g/d·head (low protein with high RPAA, T3). At the end of the experiment, the feces and urine of dairy bulls were collected for three consecutive days. Blood and rumen fluid were collected before morning feeding, and liver samples were collected after slaughtering. The results showed that the average daily gain (ADG) of bulls in the T3 group was higher than those in D1 (
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