Evidence map›Paper›PMID 36899678›Full record

ArticleAnimals : an open access journal from MDPI2023

Regulatory Role of microRNA of Milk Exosomes in Mastitis of Dairy Cows.

Bruno Stefanon, Michela Cintio, Sandy Sgorlon, Elisa Scarsella, Danilo Licastro, Alfonso Zecconi, Monica Colitti

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Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bruno StefanonDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-7414-5830
Michela CintioDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-3078-6177
Sandy SgorlonDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.
Elisa ScarsellaDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-1463-4608
Danilo LicastroAREA Science Park, Padriciano, 99, 34149 Trieste, Italy.ORCID 0000-0001-8372-9355
Alfonso ZecconiOne Health Unit, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milano, Italy.ORCID 0000-0002-3127-8385
Monica ColittiDepartment of Agriculture, Food, Environmental and Animal Science, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-1775-3880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to compare the cargos of miRNA in exosomes isolated from the milk of healthy (H) cows, cows at risk of mastitis (ARM), and cows with subclinical mastitis (SCM). Based on the number of somatic cells and the percentage of polymorphonuclear cells, 10 cows were assigned to group H, 11 to group ARM, and 11 to group SCM. After isolating exosomes in milk by isoelectric precipitation and ultracentrifugation, the extracted RNA was sequenced to 50 bp long single reads, and these were mapped against Btau_5.0.1. The resulting 225 miRNAs were uploaded to the miRNet suite, and target genes for

Indexed as

cowexosomesmastitismilkmiRNA

Identifiers

PMID36899678
PMCPMC10000098

What OpenQuestion holds

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LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.