Evidence map›Paper›PMID 36899630›Full record

ArticleAnimals : an open access journal from MDPI2023

Fetal Growth and Osteogenesis Dynamics during Early Development in the Ovine Species.

Sara Succu, Efisiangelo Contu, Daniela Bebbere, Sergio Domenico Gadau, Laura Falchi, Stefano Mario Nieddu, Sergio Ledda

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In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Frontiers in veterinary science · 2026
    Article
  2. Article
  3. Article
  4. Fetometry in Arabian horses.Frontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara SuccuDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-4901-9904
Efisiangelo ContuIstituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.
Daniela BebbereDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-5277-5698
Sergio Domenico GadauDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-8579-3799
Laura FalchiDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Stefano Mario NiedduDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Sergio LeddaDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased knowledge of the developmental processes during gestation could provide valuable information on potential alterations in embryonic/fetal development. We examined the development of ovine conceptus between the 20th and 70th day of gestation with three convergent analyses: (1) uterus ultrasound examination and measurement (eco) of crown-rump length (CRL) and biparietal diameter (BPD) of the conceptus; (2) direct measurement (vivo) of CRL and BPD of the conceptus outside the uterus (3) osteo-cartilage dynamics during development by differential staining. No significant differences were observed between eco and vivo measurements for CRL and BPD in all examined concepti. CRL and BPD, instead, showed a significant positive linear correlation with gestational age. The study of osteogenesis dynamics has demonstrated a completely cartilaginous ovine fetus at up to 35 days of gestation. The ossification begins in the skull (40th day) and is almost complete between the 65th and the 70th of pregnancy. Our study highlighted that CRL and BPD are accurate parameters for gestational age estimation in the first part of sheep pregnancy and provides an overview of osteochondral temporal dynamics. Furthermore, tibia ossification is a valid parameter to estimate fetal age by ultrasound.

Indexed as

osteogenesis dynamicsprenatal growthsheepultrasound

Identifiers

PMID36899630
PMCPMC10000038

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.