Evidence map›Paper›PMID 36899362›Full record

ArticleRespiratory research2023

Childhood asthma diagnoses declined during the COVID-19 pandemic in the United States.

Daniel B Horton, Amanda L Neikirk, Yiling Yang, Cecilia Huang, Reynold A Panettieri, Stephen Crystal, Brian L Strom, Lauren E Parlett

Open access · goldAbstract readLetter
In one paragraph

Article in Respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Incidence of New Asthma and Asthma Exacerbation Pre- and Post-COVID-19 Pandemic in the United States.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  2. Article
  3. Review
  4. Beyond respiratory syncytial virus and rhinovirus: The other viral respiratory bandits.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  5. New Diagnoses of Juvenile Idiopathic Arthritis Early in the COVID-19 Pandemic: Analysis of a Large United States Commercial Insurance Database.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Daniel B HortonDepartment of Pediatrics, Rutgers Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA. daniel.horton@rutgers.edu.
Amanda L NeikirkHealthCore Inc., Wilmington, DE, USA.
Yiling YangHealthCore Inc., Wilmington, DE, USA.
Cecilia HuangCenter for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, 112 Paterson Street, New Brunswick, NJ, 08901, USA.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science, New Brunswick, NJ, USA.
Stephen CrystalRutgers Center for Health Services Research, Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA.
Brian L StromCenter for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, 112 Paterson Street, New Brunswick, NJ, 08901, USA.
Lauren E ParlettHealthCore Inc., Wilmington, DE, USA.
Wilmington University · USJohnson University · USRutgers, The State University of New Jersey · USRutgers Health

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Antibiotics, Juvenile Idiopathic Arthritis, and Antirheumatic Treatment ResponseR01AR074436 · NIAMS · RUTGERS, THE STATE UNIV OF N.J. · PI HORTON, DANIEL BENJAMIN · 2019 to 2022
$2.1M
NCATS NIH HHS UL1 TR003017NIAMS NIH HHS R01 AR074436NIEHS NIH HHS P30 ES005022Office of Extramural Research, National Institutes of Health R01AR074436Office of Extramural Research, National Institutes of Health UL1TR003017
6 · The paper itself

Abstract

backgroundPrior studies have documented declines in pediatric asthma exacerbations and asthma-related health care utilization during the COVID-19 pandemic, but less is known about the incidence of asthma during the pandemic.

methodsWe conducted a retrospective cohort study of children under age 18 without a prior diagnosis of asthma within a large US commercial claims database. Incident asthma was defined using a combination of diagnosis codes, location of services, and medication dispensing. Crude quarterly rates of asthma diagnosis per 1000 children were calculated, and the incidence rate ratio and 95% confidence interval were estimated for newly diagnosed asthma during versus before the pandemic using negative binomial regression, adjusted for age, sex, region, and season.

resultsCompared with 3 years prior to the pandemic, crude incident diagnosis rates of asthma decreased by 52% across the first four quarters of the US pandemic. The covariate-adjusted pandemic-associated incidence rate ratio was 0.47 (95% confidence interval 0.43, 0.51).

conclusionsNew diagnoses of childhood asthma in the US declined by half during the first year of the pandemic. These findings raise important questions whether pandemic-related changes in infectious or other triggers truly altered the incidence of childhood asthma beyond the well-described disruptions in healthcare access.

Indexed as

AsthmaCOVID-19AdolescentChildHumansPandemicsPatient Acceptance of Health CareRetrospective StudiesUnited StatesAdolescentAsthma/epidemiologyChildDatabasePandemics

Identifiers

PMID36899362
PMCPMC9999066
OpenAlexW4323851054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.