Evidence map›Paper›PMID 36899359›Full record

ArticleBMC public health2023

Factors associated with severity and anatomical distribution of diabetic foot ulcer in Uganda: a multicenter cross-sectional study.

Bienfait Mumbere Vahwere, Robinson Ssebuufu, Alice Namatovu, Patrick Kyamanywa, Ibrahim Ntulume, Isaac Mugwano, Theophilus Pius, Franck Katembo Sikakulya, Okedi Francis Xaviour, Yusuf Mulumba and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Bienfait Mumbere VahwereKampala International University, Western Campus, Kampala, Uganda.
Robinson SsebuufuMengo Hospital, Kampala, Uganda. rssebuufu@gmail.com.
Alice NamatovuCollege of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Patrick KyamanywaUganda Martyrs University, Nkozi, Uganda.
Ibrahim NtulumeKampala International University, Western Campus, Kampala, Uganda.
Isaac MugwanoFortportal Regional Referral Hospital, Fort portal, Uganda.
Theophilus PiusKampala International University, Western Campus, Kampala, Uganda.
Franck Katembo SikakulyaKampala International University, Western Campus, Kampala, Uganda.
Okedi Francis XaviourKampala International University, Western Campus, Kampala, Uganda.
Yusuf MulumbaUganda Cancer Institute, Kampala, Uganda.
Soria JorgeKampala International University, Western Campus, Kampala, Uganda.
Gidio AgabaKiruddu National Referral Hospital, Kampala, Uganda.
George William NasinyamaUnicaf University in Uganda, Kampala, Uganda.
Kampala International University · UGMakerere University · UGFort Portal Hospital · UGMengo Hospital · UGUganda Cancer Institute · UGUganda Martyrs University · UGUniversité Catholique du Graben · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic foot ulcer (DFU) is a devastating complication of diabetes mellitus (DM) that is associated with increased mortality, morbidity, amputation rate and economic burden. This study aimed at identifying the anatomical distribution and factors associated with severity of DFU in Uganda. METHODOLOGY: This was a multicenter cross-sectional study conducted in seven selected referral hospitals in Uganda. A total of 117 patients with DFU were enrolled in this study between November 2021 and January 2022. Descriptive analysis and modified Poisson regression analysis were performed at 95% confidence interval; factors with p-value < 0.2 at bivariate analysis were considered for multivariate analysis.

resultsThe right foot was affected in 47.9% (n = 56) of patients, 44.4% (n = 52) had the DFU on the plantar region of the foot and 47.9% (n = 56) had an ulcer of > 5 cm in diameter. The majority (50.4%, n = 59) of patients had one ulcer. 59.8% (n = 69) had severe DFU, 61.5% (n = 72) were female and 76.9% had uncontrolled blood sugar. The mean age in years was 57.5 (standard deviation 15.2 years). Primary (p = 0.011) and secondary (p < 0.001) school educational levels, moderate (p = 0.003) and severe visual loss (p = 0.011), 2 ulcers on one foot (p = 0.011), and eating vegetables regularly were protective against developing severe DFU (p = 0.03). Severity of DFU was 3.4 and 2.7 times more prevalent in patients with mild and moderate neuropathies (p < 0.01), respectively. Also, severity was 1.5 and 2.5 higher in patients with DFU of 5-10 cm (p = 0.047) and in those with > 10 cm diameter (p = 0.002), respectively.

conclusionMost DFU were located on the right foot and on the plantar region of the foot. The anatomical location was not associated with DFU severity. Neuropathies and ulcers of > 5 cm diameter were associated with severe DFU but primary and secondary school education level and eating vegetables were protective. Early management of the precipitating factors is important to reduce the burden of DFU.

Indexed as

Diabetes MellitusDiabetic FootCross-Sectional StudiesFemaleHumansMaleRisk FactorsUgandaDiabetic foot ulcerSeverityUganda

Identifiers

PMID36899359
PMCPMC9999659
OpenAlexW4323920871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.