Evidence map›Paper›PMID 36899160›Full record

ArticleNature methods2023

Subcellular omics: a new frontier pushing the limits of resolution, complexity and throughput.

James Eberwine, Junhyong Kim, Ron C Anafi, Steven Brem, Maja Bucan, Stephen A Fisher, M Sean Grady, Amy E Herr, David Issadore, Hyejoong Jeong and 8 more

Abstract read
In one paragraph

Article in Nature methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. How defective mitochondrial electrical activity leads to inherited blindness.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

James Eberwine *Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. eberwine@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-9363-0858
Junhyong Kim *Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA. Junhyong@sas.upenn.edu.ORCID http://orcid.org/0000-0002-7726-8246
Ron C AnafiDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Steven BremDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Maja BucanDepartment of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Stephen A FisherDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
M Sean GradyDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Amy E HerrDepartment of Bioengineering, University of California at Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-6906-2985
David IssadoreDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Hyejoong JeongDepartment of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.
HyunBum KimDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Daeyeon LeeDepartment of Chemical and Biomolecular Engineering, , University of Pennsylvania, Philadelphia, PA, USA.
Stanislav RubakhinDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID http://orcid.org/0000-0003-0437-1493
Jai-Yoon SulDepartment of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jonathan V SweedlerDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.ORCID http://orcid.org/0000-0003-3107-9922
John A WolfDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kenneth S ZaretDepartment of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-8932-3145
James ZouDepartment of Biomedical Data Science, Stanford University, Stanford, CA, USA.

Funding

Center for Sub-Cellular GenomicsRM1HG010023 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H, KIM, JUNHYONG · 2018 to 2022
$11.0M
The Secret Lives of RNA: The In Vivo 3D-Structural Logic of Single Neuron RNA MetabolismDP1AA028409 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H · 2019 to 2023
$5.7M
NHGRI NIH HHS RM1 HG010023NIAAA NIH HHS DP1 AA028409
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GenomicsSingle-Cell Analysis

Identifiers

PMID36899160
PMCPMC10049458

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.