Evidence map›Paper›PMID 36899144›Full record

SynthesisEuropean journal of pediatrics2023

Effects of intrauterine exposure to SARS-CoV-2 on infants' development: a rapid review and meta-analysis.

Gabriela Soutto Mayor Assumpção Pinheiro, Rayany Cristina de Souza, Vivian Mara Gonçalves de Oliveira Azevedo, Nathalia Sernizon Guimarães, Laura Gregório Pires, Stela Maris Aguiar Lemos, Claudia Regina Lindgren Alves

Open access · bronzeAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Impact of SARS-Cov-2 exposure during pregnancy on child neurodevelopment: systematic review and meta-analysis.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
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  4. Perinatal hardship and infant neurodevelopment: insights from a global pandemic.Journal of child psychology and psychiatry, and allied disciplines · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gabriela Soutto Mayor Assumpção PinheiroPostgraduate Program in Health Sciences - Child and Adolescent Health, Medicine School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0003-3585-1107
Rayany Cristina de SouzaPostgraduate Program in Health Sciences, Medicine School, Universidade Federal de Uberlândia (UFU), Uberlândia, Brazil.ORCID http://orcid.org/0000-0002-4396-9167
Vivian Mara Gonçalves de Oliveira AzevedoPhysical Education and Physiotherapy School, Universidade Federal de Uberlândia (UFU), Uberlândia, Brazil.ORCID http://orcid.org/0000-0002-7514-1508
Nathalia Sernizon GuimarãesFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0002-0487-0500
Laura Gregório PiresMedicine School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0003-4004-0296
Stela Maris Aguiar LemosSpeech Therapy and Audiology Department, Medicine School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.ORCID http://orcid.org/0000-0003-4104-5179
Claudia Regina Lindgren AlvesPediatrics Department, Medicine School, Universidade Federal de Minas Gerais (UFMG), Av. Alfredo Balena, 190/247, Belo Horizonte, Minas Gerais, 30130100, Brazil. lindgrenalves@gmail.com.ORCID http://orcid.org/0000-0002-0885-1729
Universidade Federal de Minas Gerais · BRUniversidade Federal de Uberlândia · BRFaculdade de Ciências Médicas de Minas Gerais · BR

Funding

Coordination for the Improvement of Higher Education Personnel (CAPES) 88887.621971/2021-00Coordination for the Improvement of Higher Education Personnel (CAPES) 88887.653427/2021-00National Council for Scientific and Technological Development (CNPq) 409205/2021-4Research Support Foundation of the State of Minas Gerais (FAPEMIG) APQ-01928-21Research Support Foundation of the State of Minas Gerais (FAPEMIG) ID 12289
6 · The paper itself

Abstract

Potential medium- and long-term neurodevelopmental sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy have not been ruled out. We aimed to systematically review and summarize the evidence regarding the effects of intrauterine exposure to SARS-CoV-2 on infant development and behavior. Scopus, PubMed, Web of Science, CINAHL, and PsycNet databases were searched for studies published up to February 6, 2023, investigating the effects of gestational SARS-CoV-2 on infant development and behavior. We performed narrative synthesis according to updated protocols. Studies using comparison groups and with the Ages and Stages Questionnaires-Third Edition (ASQ-3) scores available were included in a meta-analysis performed according to Cochrane protocols. We used the Newcastle-Ottawa Quality Assessment Scale to analyze the risk of bias. Heterogeneity was calculated using the I

Indexed as

COVID-19SARS-CoV-2ChildChild DevelopmentFemaleHumansInfantPandemicsPregnancyPregnancy OutcomeChild developmentCOVID-19InfantMaternal exposurePregnancySARS-CoV-2

Identifiers

PMID36899144
PMCPMC10005921
OpenAlexW4323921029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.