Evidence map›Paper›PMID 36899126›Full record

ArticlePediatric research2023

Neighborhood disparities and the burden of lead poisoning.

Marissa Hauptman, Michelle L Rogers, Matthew Scarpaci, Barbara Morin, Patrick M Vivier

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  7. Visualizing Parcel-Level Lead Risk Using an Exterior Housing-Based Index.International journal of environmental research and public health · 2024
    Article
  8. Article
  9. Pediatric Lead Chelation Managed During Critical Medication Shortages: Case Report and Literature Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Marissa Hauptman *Division of General Pediatrics, Boston Children's Hospital, Boston, MA, USA. Marissa.Hauptman@childrens.harvard.edu.
Michelle L Rogers *Hassenfeld Child Health Innovation Institute, Brown University, Providence, RI, USA.
Matthew ScarpaciHassenfeld Child Health Innovation Institute, Brown University, Providence, RI, USA.
Barbara MorinCenter for Healthy Homes and Environment, Rhode Island Department of Health, Providence, RI, USA.
Patrick M VivierHassenfeld Child Health Innovation Institute, Brown University, Providence, RI, USA.
Brown University · USBoston Children's Hospital · USRhode Island Department of Health · USTufts University · US

Funding

Air Pollution, Stress and Asthma Morbidity Risk: Role of Biological and Geospatial MarkersK23ES031663 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI HAUPTMAN, MARISSA · 2021 to 2025
$984k
NIEHS NIH HHS K23 ES031663
6 · The paper itself

Abstract

backgroundTo assess the persistence of neighborhood-level lead poisoning disparities in Rhode Island.

methodsRhode Island Department of Health blood lead levels (BLL) collected from 2006-2019 were linked to census block group rates of poverty and housing built pre-1950. We computed multivariate logistic regression models of elevated BLLs (≥5 µg/dL and ≥10 µg/dL).

resultsOf the 197,384 study children, 12.9% had BLLs ≥5 µg/dL and 2.3% had BLLs ≥10 µg/dL. The proportion of children with BLL ≥ 5 µg/dL increased across quintiles of poverty and old housing. The odds ratio for highest quintiles was 1.44 (95% CI: 1.29, 1.60) and 1.92 (95% CI: 1.70, 2.17) for poverty and pre-1950 housing, respectively. A significant temporal decline was observed for BLL ≥ 5 µg/dL (2006: 20.5%, 2019: 3.6%). Disparities narrowed over the study period across quintiles of poverty and old housing with a similar trend appearing in the proportion of children with BLL ≥ 10 µg/dL.

conclusionDespite tremendous progress in reducing lead exposure, substantial neighborhood disparities in lead poisoning persist. These findings provide valuable considerations for primary childhood lead exposure prevention. IMPACT: Through linkage of Rhode Island Department of Health childhood lead poisoning and census data, this study captures neighborhood-level disparities in lead poisoning from 2006-2019. This study demonstrates that the odds of lead poisoning increased in a stepwise fashion for neighborhood quintiles of poverty and housing built pre-1950. While the magnitude of lead poisoning disparities narrowed across quintiles of poverty and old housing, disparities persist. Children's exposure to sources of lead contamination continues to be an important public health concern. The burden of lead poisoning is not equally distributed among all children or communities.

Indexed as

LeadLead PoisoningChildEnvironmental ExposureHumansInfantPovertyResidence CharacteristicsRhode IslandLead

Identifiers

PMID36899126
PMCPMC10000346
OpenAlexW4323833120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.