Evidence map›Paper›PMID 36899109›Full record

ArticleEye (London, England)2023

The incidence and prevalence of recurrent corneal erosion syndrome in London, UK.

Shafi Balal, Abdus Samad Ansari, Peng Yong Sim, Harun Juwale, Mohammed Aamir Ismailjee, Rohan Hussain, Sajjad Ahmad, Anant Sharma

Open access · greenAbstract read
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Shafi BalalMoorfields Eye Hospital, 162 City Road, London, UK. Shafi.balal@nhs.net.ORCID 0000-0001-7683-2741
Abdus Samad AnsariSection of Academic Ophthalmology, School of Life Course Sciences, FoLSM, King's College London, London, UK.
Peng Yong SimMoorfields Eye Hospital, 162 City Road, London, UK.
Harun JuwaleThe University of Manchester, Oxford Road, Manchester, UK.
Mohammed Aamir IsmailjeeMoorfields Eye Hospital, 162 City Road, London, UK.ORCID 0000-0002-4413-6976
Rohan HussainMoorfields Eye Hospital, 162 City Road, London, UK.ORCID 0000-0002-4082-5651
Sajjad AhmadMoorfields Eye Hospital, 162 City Road, London, UK.ORCID 0000-0002-8336-4314
Anant SharmaMoorfields Eye Hospital, 162 City Road, London, UK.
Moorfields Eye Hospital · GBInstitute of Ophthalmology · MXKing's College London · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent corneal erosion syndrome (RCES) is caused by repeated episodes of corneal epithelial breakdown due to improper adherence of the corneal epithelium to the underlying basement membrane. The most common aetiologies are corneal dystrophy or previous superficial ocular trauma. The incidence and prevalence of the condition is currently unknown. This study aimed to determine the incidence and prevalence of RCES within the London population over a 5-year period in order to better inform clinicians and evaluate how this condition affects ophthalmic service provision.

methodsA retrospective cohort study over a 5-year period reviewed 487,690 emergency room patient attendances at Moorfields Eye Hospital (MEH) London between 1 January 2015 and 31 December 2019. MEH caters for a local population comprising of around ten regional clinical commissioning groups (CCGs). The data for this study were collected using OpenEyes

resultsOut of 330,684 patients, 3623 patients were given a new diagnosis of RCES by the emergency ophthalmology services, and from these, 1056 patients attended outpatient follow-up. The crude annual incidence of RCES was estimated at 25.4 per 100,000, with a crude prevalence rate of 0.96%. There was no statistical difference in annual incidence across the 5-year period.

conclusionsThe period prevalence of 0.96% shows that RCES is not uncommon. There was also a stable annual incidence over the 5-year period, showing no changing trend over the study period. However, identifying the true incidence and period prevalence is a challenging task, as minor cases may heal prior to examination by an ophthalmologist. It is highly likely that RCES is underdiagnosed and therefore underreported.

Indexed as

Corneal Dystrophies, HereditaryCorneal EdemaCorneal UlcerHumansIncidenceLondonPrevalenceRetrospective StudiesSyndrome

Identifiers

PMID36899109
PMCPMC10564719
OpenAlexW4323857508

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.