Evidence map›Paper›PMID 36898988›Full record

ArticleNature communications2023

The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei.

Ravish Rashpa, Natacha Klages, Domitille Schvartz, Carla Pasquarello, Mathieu Brochet

Open access · goldFull text read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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  13. Atlas ofeLife · 2023
    Article
  14. Atlas ofbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ravish RashpaUniversity of Geneva, Faculty of Medicine, Department of Microbiology and Molecular Medicine, Geneva, Switzerland. Ravish.Rashpa@unige.ch.ORCID 0000-0001-7144-0829
Natacha KlagesUniversity of Geneva, Faculty of Medicine, Department of Microbiology and Molecular Medicine, Geneva, Switzerland.
Domitille SchvartzUniversity of Geneva, Faculty of Medicine, Proteomics Core Facility, Geneva, Switzerland.
Carla PasquarelloUniversity of Geneva, Faculty of Medicine, Proteomics Core Facility, Geneva, Switzerland.
Mathieu BrochetUniversity of Geneva, Faculty of Medicine, Department of Microbiology and Molecular Medicine, Geneva, Switzerland. Mathieu.Brochet@unige.ch.ORCID 0000-0003-3911-5537
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria-causing parasites of the Plasmodium genus undergo multiple developmental phases in the human and the mosquito hosts, regulated by various post-translational modifications. While ubiquitination by multi-component E3 ligases is key to regulate a wide range of cellular processes in eukaryotes, little is known about its role in Plasmodium. Here we show that Plasmodium berghei expresses a conserved SKP1/Cullin1/FBXO1 (SCF

Indexed as

Plasmodium bergheiCullin ProteinsCyclinsErythrocytesHumansProtein BindingS-Phase Kinase-Associated ProteinsUbiquitinationCACUL1 protein, humanCCNF protein, humanCullin ProteinsCyclinsSKP1 protein, humanS-Phase Kinase-Associated Proteins

Identifiers

PMID36898988
PMCPMC10006092
OpenAlexW4323858116

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read150
table measurements read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.