Evidence map›Paper›PMID 36898842›Full record

ArticleTobacco control2024

Multistate transition modelling of e-cigarette use and cigarette smoking among youth in the UK.

Jennie C Parnham, Charlotte Vrinten, Márta K Radó, Alex Bottle, Filippos T Filippidis, Anthony A Laverty

Abstract read
In one paragraph

Article in Tobacco control, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Continuous associations of the brief Wisconsin Inventory of Smoking Dependence Motives with transitions between cigarette and e-cigarette use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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  5. Urinary Tobacco and Nicotine Exposure Biomarkers as Predictors of Transitions between Cigarette and e-Cigarette Use in the Exhale Longitudinal Cohort Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennie C ParnhamPrimary Care and Public Health, Imperial College London, London, UK j.parnham18@imperial.ac.uk.ORCID 0000-0002-4385-2153
Charlotte VrintenPrimary Care and Public Health, Imperial College London, London, UK.ORCID 0000-0002-6187-0638
Márta K RadóDepartment of Management and Engineering, Institute for Analytical Sociology, Linköping University, Linköping, Sweden.
Alex BottleDr Foster Unit, School of Public Health, Imperial College London, London, UK.
Filippos T FilippidisPrimary Care and Public Health, Imperial College London, London, UK.ORCID 0000-0002-2101-2559
Anthony A LavertyPrimary Care and Public Health, Imperial College London, London, UK.ORCID 0000-0003-1318-8439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionE-cigarette use remains a controversial topic, with questions over how people transition between e-cigarette use and cigarette smoking. This paper examined transitions into and out of nicotine product use in a representative sample of UK youth.

methodsWe used Markov multistate transition probability models on data from 10 229 participants (10-25 years old) in the UK Household Longitudinal Study (2015-2021). We used four product use states ('never', 'non-current use', 'e-cigarette only' and 'smoking and dual use') and estimated likelihood of transitions according to sociodemographic characteristics.

resultsAmong participants who had never used nicotine products, most were still non-users a year later (92.9% probability; 95% CI 92.6%, 93.2%); a small proportion transitioned to using e-cigarettes only (4.0%; 95% CI 3.7%, 4.2%) and cigarettes (2.2%; 95% CI 2.0%, 2.4%). Those aged 14-17 years were the most likely to start using a nicotine product. E-cigarette use was less persistent overtime than cigarette smoking, with a 59.1% probability (95% CI 56.9%, 61.0%) of e-cigarette users still using after 1 year compared with 73.8% (95% CI 72.1%, 75.4%) for cigarette smoking. However, there was a 14% probability (95% CI 12.8%, 16.2%) that e-cigarette users went onto smoke cigarettes after 1 year, rising to 25% (95% CI 23%, 27%) after 3 years.

conclusionThis study found that although overall nicotine product use was relatively rare, participants were more likely to experiment with e-cigarette use than cigarette smoking. This was mostly not persistent over time; however, approximately one in seven transitioned to cigarette smoking. Regulators should aim to deter all nicotine product use among children.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsVapingAdolescentAdultChildFemaleHumansLongitudinal StudiesMaleMarkov ChainsUnited KingdomYoung AdultCo-substance useElectronic nicotine delivery devicesPriority/special populations

Identifiers

PMID36898842
PMCPMC11228222

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.