Evidence map›Paper›PMID 36898398›Full record

ReviewThe Lancet. Microbe2023

Mpox respiratory transmission: the state of the evidence.

Amy Beeson, Ashley Styczynski, Christina L Hutson, Florence Whitehill, Kristina M Angelo, Faisal S Minhaj, Clint Morgan, Kaitlyn Ciampaglio, Mary G Reynolds, Andrea M McCollum and 1 more

Abstract readReview
In one paragraph

Review in The Lancet. Microbe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Mpox Airborne Transmission: A Systematic Review.Reviews in medical virology · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Mpox (Monkeypox) in Pregnancy Updates.Health science reports · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Amy BeesonMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Ashley StyczynskiMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Christina L HutsonMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Florence WhitehillMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Kristina M AngeloMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Faisal S MinhajMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Clint MorganMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Kaitlyn CiampaglioMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mary G ReynoldsMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Andrea M McCollumMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sarah Anne J GuagliardoMpox Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: sguagliardo@cdc.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relative contribution of the respiratory route to transmission of mpox (formerly known as monkeypox) is unclear. We review the evidence for respiratory transmission of monkeypox virus (MPXV), examining key works from animal models, human outbreaks and case reports, and environmental studies. Laboratory experiments have initiated MPXV infection in animals via respiratory routes. Some animal-to-animal respiratory transmission has been shown in controlled studies, and environmental sampling studies have detected airborne MPXV. Reports from real-life outbreaks demonstrate that transmission is associated with close contact, and although it is difficult to infer the route of MPXV acquisition in individual case reports, so far respiratory transmission has not been specifically implicated. Based on the available evidence, the likelihood of human-to-human MPXV respiratory transmission appears to be low; however, studies should continue to assess this possibility.

Indexed as

Mpox, MonkeypoxAnimalsHumansModels, AnimalMonkeypox virusProbability

Identifiers

PMID36898398
PMCPMC9991082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.